Press Releases

Scientists reduced levels of BRCA1 in mouse brains and in neurons in a dish to investigate the role of the protein in dementia.

DNA repair factor linked to breast cancer may also play a role in Alzheimer's disease

Monday, November 30, 2015

Mutant forms of breast cancer factor 1 (BRCA1) are associated with breast and ovarian cancers but according to new findings, in the brain the normal BRCA1 gene product may also be linked to Alzheimer's disease. The results, published in Nature Communications, suggest that low levels of BRCA1...

Scientists mapped the brain circuits that allow flies to react to temperature changes.

Study shows how fruit flies beat the heat (and cold)

Monday, November 23, 2015

Humans aren't the only ones that take shelter when the weather turns unpleasant. A team of researchers at Northwestern University's Department of Neurobiology has mapped the neural circuits that allow flies to avoid uncomfortable temperatures.

Injecting a shot of genes into the brain’s ventricular plumbing system may be an effective long term method for treating neurological disorders.

Batten disease may benefit from gene therapy

Wednesday, November 11, 2015

In a study of dogs, scientists showed that a new way to deliver replacement genes may be effective at slowing the development of childhood Batten disease, a rare and fatal neurological disorder.

Adding GDF10 to neurons in a dish results in the formation of new connections between brain cells. This process may lead to recovery after stroke.

Scientists identify main component of brain repair after stroke

Wednesday, October 28, 2015

Looking at brain tissue from mice, monkeys and humans, scientists have found that a molecule known as growth and differentiation factor 10 (GDF10) is a key player in repair mechanisms following stroke. The findings suggest that GDF10 may be a potential therapy for recovery after stroke. The...

Scientists discovered how a pair of proteins work together to produce chronic itch.

An itch you just can't scratch

Tuesday, October 27, 2015

Everyone knows the best way to suppress an itch is to scratch it, but for people who suffer from skin diseases like eczema, no amount of scratching can bring relief. Fortunately, help may be on the way. Scientists from the Buck Institute for Research on Aging and the University of California,...

Scientists mapped out the brain circuitry that helps mice focus.

Study in mice shows how brain ignores distractions

Wednesday, October 21, 2015

In a study of mice, scientists discovered that a brain region called the thalamus may be critical for filtering out distractions. The study, published in Nature and partially funded by the National Institutes of Health, paves the way to understanding how defects in the thalamus might underlie...

A genetic mutation implicated in ALS and FTD prevents proteins (green) from entering and exiting the cell’s nucleus (pink).

Nuclear transport problems linked to ALS and FTD

Friday, October 16, 2015

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus,...

NIH invests $85 million for BRAIN Initiative research

Thursday, October 1, 2015

The National Institutes of Health announced its second wave of grants to support the goals of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, bringing the NIH investment to $85 million in fiscal year 2015.

Scientists studied human and mouse brains to show that genes for a seemingly inactive and inherited virus may cause ALS.

Dormant viral genes may awaken to cause ALS

Wednesday, September 30, 2015

Scientists at the National Institutes of Health (NIH) discovered that reactivation of ancient viral genes embedded in the human genome may cause the destruction of neurons in some forms of amyotrophic lateral sclerosis (ALS).

Scientists discovered that nuclear pores in astrocytes may play important roles in the brain.

Scientists uncover nuclear process in the brain that may affect disease

Monday, August 17, 2015

Every brain cell has a nucleus, or a central command station. Scientists have shown that the passage of molecules through the nucleus of a star-shaped cell, called an astrocyte, may play a critical role in health and disease. The study, published in the journal Nature Neuroscience, was partially...