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The formation of a brain is one of nature’s most staggeringly complex accomplishments. Now, Yale researchers and collaborators have devised a strategy that allows them to see this previously impenetrable process unfold in a living animal — the worm Caenorhabditis elegans, they report Feb. 24 in the journal Nature.
Using an innovative computational approach to analyze vast brain cell gene expression datasets, researchers at MIT and Sorbonne Université have found that Huntington’s disease may progress to advanced stages more because of a degradation of the cells’ health maintenance systems than because of increased damage from the disease pathology itself.
Understanding how the immune system responds to acute brain hemorrhage could open doors to identifying treatments for this devastating disease.
Protein Complex Shifts DNA Shape to Let Progenitor Cells Become Neurons
A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators.
While the human brain has over 400 miles of total vasculature, little is known about the tiny capillaries that make up much of this intricate labyrinth of blood vessels critical for delivering oxygenated blood and nutrients to billions of brain cells.
In mice, antibody removes amyloid, improves vessel function without raising risk of brain bleeds
Gladstone researchers have shown in mice that CNS B-cell lymphoma cells cluster at sites where there is a leak in the blood-brain barrier. They also found that a blood protein called fibrinogen, which normally participates in blood clotting, promotes this clustering.
Scientists at the Fralin Biomedical Research Institute at VTC have identified a new zebrafish model that could help advance glioblastoma multiforme research.
UTSA scientists have discovered it might be possible for SARS-CoV-2, the virus that causes COVID-19, to enter the human brain.