Grantees in the News

Grantees in the News

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Yale scientists capture the choreography of a developing brain

Yale School of Medicine
Wednesday, February 24, 2021

The formation of a brain is one of nature’s most staggeringly complex accomplishments.  Now, Yale researchers and collaborators have devised a strategy that allows them to see this previously impenetrable process unfold in a living animal — the worm Caenorhabditis elegans, they report Feb. 24 in the journal Nature.

Basic cell health systems wear down in Huntington’s disease, novel analysis shows

The Picower Institute for Learning and Memory at MIT
Tuesday, February 23, 2021

Using an innovative computational approach to analyze vast brain cell gene expression datasets, researchers at MIT and Sorbonne Université have found that Huntington’s disease may progress to advanced stages more because of a degradation of the cells’ health maintenance systems than because of increased damage from the disease pathology itself.

Yale Neurologists Identify Consistent Neuroinflammatory Response in ICH Patients

Yale School of Medicine
Monday, February 22, 2021

Understanding how the immune system responds to acute brain hemorrhage could open doors to identifying treatments for this devastating disease.

Key Decision Point for Brain Development Identified

University of California, San Francisco
Friday, February 19, 2021

Protein Complex Shifts DNA Shape to Let Progenitor Cells Become Neurons

Study Reveals How a Longevity Gene Protects Brain Stem Cells From Stress

Weill Cornell Medicine
Friday, February 19, 2021

A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators.

Light and Genetic Probes Untangle Dynamics of Blood Flow Through the Brain’s Vast Capillary Network

Seattle Children's
Thursday, February 18, 2021

While the human brain has over 400 miles of total vasculature, little is known about the tiny capillaries that make up much of this intricate labyrinth of blood vessels critical for delivering oxygenated blood and nutrients to billions of brain cells.

Protein linked to Alzheimer’s, strokes cleared from brain blood vessels

Washington University School of Medicine in St. Louis
Wednesday, February 17, 2021

In mice, antibody removes amyloid, improves vessel function without raising risk of brain bleeds

Blood-Clotting Protein Plays Key Role in Central Nervous System B-Cell Lymphoma

Gladstone Institute
Tuesday, February 16, 2021

Gladstone researchers have shown in mice that CNS B-cell lymphoma cells cluster at sites where there is a leak in the blood-brain barrier. They also found that a blood protein called fibrinogen, which normally participates in blood clotting, promotes this clustering.

Of mice, men – and fish: Researchers find parallels in spread of human brain cancer cells in mammals, zebrafish

Virginia Tech
Thursday, February 11, 2021

Scientists at the Fralin Biomedical Research Institute at VTC have identified a new zebrafish model that could help advance glioblastoma multiforme research.

Groundbreaking study suggests COVID-19 virus might enter human brain

The University of Texas at San Antonio
Tuesday, February 9, 2021

UTSA scientists have discovered it might be possible for SARS-CoV-2, the virus that causes COVID-19, to enter the human brain.