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Grantees in the News
Mitochondrial Disease Patients Face Difficult Road to Diagnosis
Columbia University Mailman School of Public HealthFriday, March 30, 2018
A new study documents the prolonged and difficult path patients face before they are diagnosed with mitochondrial diseases, a group of rare, debilitating genetic disorders. The study was led by researchers at Columbia University Irving Medical Center; findings appear in the journal Neurology Genetics.
Researchers Devise Decoy Molecule to Block Pain Where It Starts
University of Texas at DallasTuesday, January 16, 2018
Research performed at the University of Texas at Dallas uncovered a new method of reducing pain-associated behaviors with RNA-based medicine, creating a new class of decoy molecules that prevent the onset of pain.
Memory loss from West Nile virus may be preventable
Washington University School of Medicine in St. LouisThursday, January 11, 2018
A new study in mice suggests that the lasting neurological problems that can result from West Nile virus may be due to unresolved inflammation that hinders the brain’s ability to repair damaged neurons and grow new ones. When the inflammation was reduced by treatment with an arthritis drug, the animals’ ability to learn and remember remained sharp after West Nile disease.
Discovery deepens understanding of brain’s sensory circuitry
Brown UniversityTuesday, December 12, 2017
An exploration of the deepest and most mysterious layer of the cortex in mice has revealed new circuits that may be central to how two key regions of the brain communicate about sensation.
Electrical Stimulation in Brain Bypasses Senses, Instructs Movement
University of Rochester Medical CenterFriday, December 8, 2017
A new study authored by Marc Schieber, M.D., Ph.D., and Kevin Mazurek, Ph.D. with the University of Rochester Medical Center Department of Neurology and the Del Monte Institute for Neuroscience, which appears today in the journal Neuron, shows that very low levels of electrical stimulation delivered directly to an area of the brain responsible for motor function can instruct an appropriate response or action, essentially replacing the signals we would normally receive from the parts of the brain that process what we hear, see, and feel.
Penn Neuroscientists Construct First Whole-brain Map Showing Electrical Connections Key to Forming Memories
University of PennsylvaniaWednesday, November 22, 2017
A team of neuroscientists at the University of Pennsylvania has constructed the first whole-brain map of electrical connectivity in the brain based on data from nearly 300 neurosurgical patients with electrodes implanted directly on the brain.
To forget or to remember? Memory depends on subtle brain signals, scientists find
The Scripps Research InstituteTuesday, November 21, 2017
In a study of flies, scientists on the Florida campus of The Scripps Research Institute (TSRI), detailed how the intricate biochemical mechanism for storing scent-associated memories differs slightly from a less-understood mechanism for erasing unnecessary memories.
Good Cells Gone Bad
The Scripps Research InstituteTuesday, November 21, 2017
A new study from The Scripps Research Institute (TSRI) shows how a process in nerve cells called the S-nitrosylation (SNO) reaction—which can be caused by aging, pesticides and pollution—may contribute to Parkinson’s disease.
Spacing out after staying up late? Here’s why
University of California, Los AngelesTuesday, November 7, 2017
A new study reveals how sleep deprivation disrupts brain cells’ ability to communicate with each other.
Potential new treatment for Fragile X targets one gene to affect many
Rockefeller UniversityThursday, November 2, 2017
New research from Rockefeller University finds that inhibiting a regulatory protein alters the intricate signaling chemistry responsible for many of Fragile X Syndrome in animal models.