Genetic Modifiers: Lessons from Nervous System Disorders

Genetic Modifiers: Lessons from Nervous System Disorders

September 21, 2021
September 23, 2021

Contact: 

Maripierre P. Surpris

Contact Email: 

maripierre.surpris@nih.gov

Location: 

Virtual Event (Zoom)
Sept. 21 - 23, 2021 | 10 a.m. - 2 p.m.

Event Description: 

This workshop will bring together a diverse group of researchers with expertise in genetics, genomics, neurology, pathophysiology, and preclinical translation. Understanding genetic factors that modify the onset, progression or severity of diseases can lead to novel therapeutics, facilitate clinical trial design, and enable personalized medicine. The purpose of this workshop is to promote collaborations, confront challenges and highlight successful strategies for genetic modifier discovery, validation, and clinical implementation as part of the NIH Blueprint mission to foster transformative discoveries in neuroscience.

Sessions:

  • Day 1: Modifier discovery in human cohorts and model systems, resources available and successful analytical approaches
  • Day 2: Validation and characterization of modifiers, determining mechanisms of disease modification and mapping modifier pathways
  • Day 3: Clinical applications of modifiers as therapeutic targets, in design of clinical trials and in precision medicine

Who Can Attend:  Attendance will be free and open to all interested researchers, patients, advocacy groups

Call for Abstracts:

New / early stage investigators and trainees (students, postdocs, and clinical fellows) are encouraged to submit an online abstract. Selected abstracts will be chosen to give a 4-minute oral presentation plus Q&A during the workshop. Research in progress and incomplete stories are welcome. Please note, all participants submitting an abstract must also complete an online registration form. All submitted abstracts will be available to view on the workshop website. Please submit your abstract to: https://event.roseliassociates.com/genetic-modifiers-workshop/

Abstract Submission Guidelines:

  • Title limit: 200 characters (including spaces)
  • Body limit: 3,500 characters (including spaces)
    Please include: Research objectives, a statement of methods used, a summary of results, conclusion of the study and source of funding
  • Submission Deadline: Monday, August 16, 2021 at 11:59 pm EST. Abstracts chosen for a short talk will be notified on Thursday, September 2, 2021 and sent further instructions.

Organizers:

NIH workshop, co-chaired by:
Susan Ackerman, Ph.D. (University of California, San Diego)
Monica Justice, Ph.D. (The Hospital for Sick Children, University of Toronto)
Trudy MacKay, Ph.D. (Clemson University)
Huda Zoghbi, M.D. (Baylor College of Medicine)
Stephan Zuchner, M.D., Ph.D. (University of Miami)
Marcy E. MacDonald, Ph.D. (MGH/Harvard )