Mentored Career Awards

Clinician Research Awards

K08 - Mentored Clinical Scientist Research Career Development Award

K23 - Mentored Patient-Oriented Research Career Development Award

 

Early Faculty Awards

K01 - NINDS Faculty Development Award to Promote Diversity in Neuroscience Research

 

Postdoctoral Transition Awards

K01 - NINDS Postdoctoral Career Development Award

K22 - NINDS Advanced Postdoctoral Career Transition Award to Promote Diversity in Neuroscience Research

K22 - Career Transition Award for NINDS Intramural Clinician-Scientists

K99/R00 - NIH Pathway to Independence (PI) Award

Notices, Policy Announcements and Other Information


Clinician Research Awards

K08 - Mentored Clinical Scientist Research Career Development Award

The Mentored Clinical Scientist Development Award (K08) is designed to provide "protected time" for clinically trained individuals to participate in an intensive, supervised training program in biomedical research, including translational research, related to neurological disorders. Although the award is primarily targeted to candidates holding an MD or equivalent degree, it may also support individuals holding other health professional degrees. The award supports a 4-5 year period of supervised basic or clinical neuroscience research experience and is intended to prepare the candidate to successfully obtain an R01 or equivalent major research award by the end of the K award period. This program is intended to support applicants with a clinical doctoral degree that are within 5 years of completing their clinical training (which is defined as sequential years of residency training and clinical fellowships). Applicants that are beyond 5 years post clinical training must obtain prior written approval from the Director, Office of Training and Workforce Development to be eligible for this program.

Effort Requirements
Except for neurosurgeons (see below), candidates must devote a minimum of 75% full time professional effort to the proposed research and career development activities. The letter of institutional commitment must include a description of the candidate's non-research responsibilities, according to the following:  1/2 day = 10% of the 5 day workweek, 1 month = 8% of the year, time on call for clinical duty is not protected time for research.

For Neurosurgeons
NINDS will accept 50% full time professional effort for research and career development activities associated with the K award.  The letter of institutional commitment must describe, as above, the specific allocation of time (on a weekly and/or monthly basis) devoted to K award activities and clinical and other non-K award activities.

Salary Support
NINDS will provide up to $100,000 salary, plus appropriate fringe, per year. See NOT-OD-16-054. This policy applies to new (Type 1) applications submitted on or after February 12, 2016, and non-competing continuations (Type 5 applications) with start dates on or after October 1, 2016.

Research Support
NINDS will provide up to $51,000 per year.  See NOT-NS-13-028 for important additional information.

Institutional Support
Please pay careful attention to specific issues that must be addressed in a statement of institutional support for K08 and K23 awards.

Suggestions for a Good Career Development Plan

Who to Contact for Different Types of Questions

NOT-NS-09-015: NINDS encourages K08 award recipients to apply for independent research awards while the K08 is active.

NOT-NS-15-048: NINDS Encourages Clinicians with Excellent Pre-residency Research Publication Records to Apply for a K08 without Waiting for Post-residency Publications.

K08 Program Announcement: PA-16-191

Application Form SF 424

New Application Receipt Dates: February 12, June 12, and October 12

Renewal, Resubmission, or Revised Application Dates: March 12, July 12, November 12

Program Contact:
Stephen J. Korn, Ph.D.
Director of Training and Workforce Development
301-496-4188; Fax 301-480-1080
korns@ninds.nih.gov

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K23 - Mentored Patient-Oriented Research Career Development Award

The Mentored Patient-Oriented Research Career Development Award (K23) was created to support the career development of investigators who have made a commitment to focus their research endeavors on patient-oriented research. For the purposes of this award, patient-oriented research is defined as research conducted with human subjects (or on material of human origin such as tissues, specimens, and cognitive phenomena) for which an investigator directly interacts with human subjects. This area of research includes: 1) mechanisms of human disease; 2) therapeutic interventions; 3) clinical trials; and 4) the development of new technologies. This mechanism provides support for a period of supervised study and research for clinically trained professionals (MD or equivalent) within 5 years of completing their clinical training (which is defined as sequential years of residency training and clinical fellowships) who have the potential to develop into productive clinical investigators focusing on patient-oriented research. The project period may be 4-5 years, and is intended to prepare the candidate to successfully obtain an R01 or equivalent major research award by the end of the K award period.

Effort Requirements
Except for neurosurgeons (see below), candidates must devote a minimum of 75% full time professional effort to the proposed research and career development activities. The letter of institutional commitment must include a description of the candidate's non-research responsibilities, according to the following:  1/2 day = 10% of the 5 day workweek, 1 month = 8% of the year, time on call for clinical duty is not protected time for research.

For Neurosurgeons
NINDS will accept 50% full time professional effort for research and career development activities associated with the K award.  The letter of institutional commitment must describe, as above, the specific allocation of time (on a weekly and/or monthly basis) devoted to K award activities and clinical and other non-K award activities.

Salary Support
NINDS will provide up to $100,000 salary, plus appropriate fringe, per year. See NOT-OD-16-054. This policy applies to new (Type 1) applications due on February 12, 2016, and subsequently, as well as non-competing continuations (Type 5 applications) with start dates on or after October 1, 2016.

Research Support
NINDS will provide up to $51,000 per year.  See NOT-NS-13-028 for important additional information.

Institutional Support
Please pay careful attention to specific issues that must be addressed in a statement of institutional support for K08 and K23 awards.

Suggestions for a Good Career Development Plan

Who to Contact for Different Types of Questions

NOT-NS-09-015: NINDS encourages K23 award recipients to apply for independent research awards while the K23 is active.

NOT-NS-15-048: NINDS Encourages Clinicians with Excellent Pre-residency Research Publication Records to Apply for a K23 without Waiting for Post-residency Publications.

K23 Program Announcement: PA-16-198

Application Form SF 424

New Application Receipt Dates: February 12, June 12, and October 12

Renewal, Resubmission, or Revised Application Dates: March 12, July 12, November 12

Program Contact:
Stephen J. Korn, Ph.D.
Director of Training and Workforce Development
301-496-4188; Fax 301-480-1080
korns@ninds.nih.gov

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Early Faculty Awards

K01 - NINDS Faculty Development Award to Promote Diversity in Neuroscience Research

The purpose of the NINDS Faculty Development Award to Promote Diversity in Neuroscience Research (K01) is to provide junior faculty support and protected time (up to three years) for an intensive, supervised career development experience in neuroscience research.  The goal of the NINDS K01 is to diversify the pool of independent neuroscience research investigators and to enhance the probability of success in obtaining independent NIH or other independent research support.   Mentoring is expected to be appropriate for this stage of career and should focus on enhancing tenure track (or equivalent) activities or metrics (i.e., helping the junior faculty member to navigate institutional expectations, scientific networks, and practices that are relevant to productivity and advancement at the institution).  Individuals from backgrounds underrepresented in biomedical research are eligible for support under this award if they have doctoral research degrees (Ph.D. or equivalent) and are in the first 3 years of a faculty tenure-track or equivalent position at the time of award.

Salary and Research Costs: Salary up to $95,000 per year plus related fringe benefits will be provided. A research allowance of up to $100,000 per year will be provided. K01 award recipients are encouraged to apply for independent research awards while the K award is active, and should consult with Dr. Michelle Jones-London for budget guidance in this process.

NINDS no longer utilizes the K01 mechanism for re-entry.  NINDS uses the Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers program for support of Re-Entry Candidates (see Notice NOT-NS-11-013).

New Application Receipt Dates: February 12, June 12, and October 12

Renewal, Resubmission, or Revised Application Dates: March 12, July 12, November 12

Program Contact:
Michelle Jones-London, Ph.D.
Chief, Office of Programs to Enhance Neuroscience Workforce Diversity (OPEN-WD)
301-451-7966; Fax 301-594-5929
jonesmiche@ninds.nih.gov

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Postdoctoral Transition Awards

K01 - NINDS Postdoctoral Career Development Award

Eligibility:  Postdoctoral fellows who are in years 2 through 4 of cumulative postdoctoral research experience are eligible to apply.

Duration of Support:  Postdoctoral fellows can be supported within the first 6 years of cumulative postdoctoral research experience. For example, if the candidate has 36 months of cumulative postdoctoral research experience at the time of award, the maximum award duration would be 36 months.

Who is this K01 for?  The K01 is for a well-trained individual who is in a mentored postdoctoral research position, and wants to work in that environment for several years. The project should be one that the candidate designed in consultation with the mentor and will subsequently take to an independent research position.  The K01 is intended to support the development of an impactful research project, which, combined with a thorough career development plan, will prepare the candidate to launch a successful, impactful independent research career. By the end of the K01 award period, the individual should have a well-developed, potentially impactful project that can be continued by the awardee in the independent research position. The K01 is NOT designed to support postdoctoral fellows who are simply conducting research previously proposed in the mentor’s research grant, for which the applicant has contributed little original input into the research questions or design.

This K01 is NOT a substitute for an F32. The expectation in review regarding sophistication and presentation will be similar to that of a K99/R00 – the K01 is for well-trained candidates, with a strong research track record, who have demonstrated the ability to conduct rigorous research, and who are working on a potentially impactful project with an outstanding mentor. There is an expectation of high quality preliminary data and a demonstration of creativity and/or innovation. The research project should be viewed as original, highly significant and in the hands of a candidate who, under the guidance of the mentor, will gain the tools to successfully conduct the research. By the end of the K01 period, the candidate should be poised to be a creative, innovative, rigorous investigator in his/her field and to successfully launch an independent research program.

Are applicants more likely to get a K01 if they delay applying until they have published in the proposed laboratory?  As described in the funding opportunity announcement (FOA) for this K01, “applications are strongly encouraged from candidates who are at the earlier end of the eligibility window so that they will have sufficient time to accomplish the career development goals of the award.”  Of course, applicants who apply earlier may not yet have publications in their current postdoctoral laboratory.  For an original, highly significant project, one year is generally enough time to collect high quality data, formulate clear, rigorous experimental plans and goals, and confirm that a project will yield important fruit, yet perhaps not time enough to publish a compelling, impactful paper. Similarly, it may be that the candidate is working on a complex project that requires several years of research prior to publication.  So having a publication from the proposed postdoctoral laboratory is not a requirement for a successful NINDS postdoctoral K01 application. As for all grant applications, reviewers will have an expectation that productivity is appropriate given the research area, project complexity and time spent on the project.  In some cases, reviewers may think that the candidate should have published by the time of application. In other cases, reviewers will likely consider it unreasonable to expect publications from the proposed postdoctoral laboratory by the time of application. (Note that successful candidates will be expected to have demonstrated the ability to lead a research project and publish one or more excellent papers at some point prior to application, and to have a record of productivity reflective of a high level of accomplishment appropriate to their current career stage).

Potential candidates should read the FOA carefully. Applicants are strongly advised to carefully read the entire FOA so they will know exactly what is required. As with all NIH FOAs, reading all sections, including the review criteria, provides great insight into what reviewers will be evaluating.

What is the difference between the K01 and K99/R00?

Both of these mechanisms are for the support of well-trained postdoctoral fellows who have original, innovative approaches to significant research questions and who conduct rigorous, high quality research that has the potential for high impact. The K01 is for individuals who want to devote a significant period of time, under the guidance of an outstanding mentor, to develop an outstanding project. The K99/R00 is for individuals who are finishing up their postdoctoral training, have already developed an outstanding research project and are nearly ready to transition to a tenure-track or equivalent position.

Can I receive both a K01 and a K99/R00?

No.

Can the K01 be transferred to a faculty position?

The K01 is intended to support activities under the guidance of a postdoctoral mentor. However, after a minimum of 18 months of K01 support, if the K01 scholar transitions to an independent faculty position, remaining time (up to 12 months maximum) on the award may be used to support the scholar in the independent position.

Can one apply for a K award to move from a first postdoc to a second postdoc? Which is better for this, a K01 or a K99/R00?

One could apply for either for this purpose. The issue to think about is, how does the award match up with your plan? For either award, your end goal should be to obtain an independent research position. If you wish to spend more than 2 years in the new laboratory, perhaps developing a complex project that will form the basis of your independent research, the K01 may be advantageous. If you will obtain the training and results you need for independence within 2 years of entering the new lab, the K99/R00 may be more appropriate. Keep in mind, however, that whereas both grants can be transferred to a faculty position, the rules for transfer, and the value of the transferred award, will be different.
 

See NIH Program Announcement:  PAR-17-145

Application Form SF 424

Application Receipt Dates:  Initial Receipt Date - April 4, 2017, then standard receipt dates apply starting June 12, 2017

Program Contact:
Stephen J. Korn, Ph.D.
Director of Training and Workforce Development
301-496-4188; Fax 301-480-1080
korns@ninds.nih.gov

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K22 - NINDS Advanced Postdoctoral Career Transition Award to Promote Diversity in Neuroscience Research

This opportunity provides individuals from diverse backgrounds with strong training in neuroscience with the resources and tools that will help facilitate a transition to a stable and productive independent research position. Individuals from diverse backgrounds underrepresented in neuroscience research are eligible for support under this award if they have doctoral research degrees (Ph.D., Ph.D./M.D. or equivalent) and between 2 and 5 years of postdoctoral research experience at the time of application.

Salary and Research Costs: During Phase I NIH will contribute salary commensurate with the applicant institution's salary structure for persons of equivalent qualifications, experience, and rank, up to $50,000 plus fringe benefits per year. During Phase II, NIH will contribute up to $95,000, commensurate with salary and effort, as well as fringe benefits, toward the salary of the career award recipient. NIH will contribute up to $25,000 in Phase I and $100,000 in Phase 2 per year toward the research and career development costs of the award recipient, which must be justified and consistent with the stage of development of the candidate and the proportion of time to be spent in research or career development activities.

See NIH Program Announcement: PAR-16-220

Application Form SF 424

Resources:

The new expiration date for this program announcement is May 8, 2019

New Application Receipt Dates: February 12, June 12, and October 12

Renewal, Resubmission, or Revised Application Dates: March 12, July 12, November 12

Program Contact:
Michelle Jones-London, Ph.D.
Chief, Office of Programs to Enhance Neuroscience Workforce Diversity (OPEN-WD)
301-451-7966; Fax 301-594-5929
jonesmiche@ninds.nih.gov

 

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K22 - Career Transition Award for NINDS Intramural Clinician-Scientists

The objective of the NIH Career Transition Award (K22) is to provide support to outstanding basic or clinical investigators to develop their independent research skills through a two phase program: an initial period involving an intramural appointment at the NIH and a final period of support at an extramural institution. This NINDS K22 is specifically designed to facilitate the transition of NINDS intramural neurologist- and neurosurgeon-scientists to independent, academic faculty positions that support clinician-scientists to engage in independently funded scientific research as well as clinical activities.

Salary and Research Costs: During the intramural support years, salary will be consistent with that provided by the intramural program for other investigators in the same position.  The NINDS intramural program will provide $25,000 per year toward research career development costs of the award recipient.   During the extramural support years, NINDS will contribute up to $100,000  per year toward salary and $50,000  per year toward research development costs of the award recipient, which must be justified and consistent with the stage of development of the candidate and the proportion of time to be spent in research or career development activities.

See NIH Program Announcement:  PAR-16-340

Application Form SF 424

New Application Receipt Dates: February 12, June 12, and October 12

Renewal, Resubmission, or Revised Application Dates: March 12, July 12, November 12

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K99/R00 - NIH Pathway to Independence (PI) Award

NIH New Investigators Program

The Pathway to Independence Award is uniquely designed to facilitate the transition of outstanding postdoctoral candidates from mentored to independent research positions. The award contains two components, a mentored (K99) phase that can last up to 2 years and an independent (R00) phase, which will have a duration of 3 years. The objective of the program is to facilitate research independence earlier in an investigator's career. Investigators complete supervised research, and apply for an independent research faculty position, during the mentored phase of the award. Activation of the independent award phase is administrative, and is contingent upon the investigator securing an independent research position. For applications due February 12, 2014 and beyond, eligible candidates will have no more than 4 years of postdoctoral research at the time of application (initial or amended). Eligible applicants will currently be in a mentored postdoctoral position, regardless of title. Review the NIH definition of a postdoctoral scholar. Award recipients are expected to obtain R01 support during the independent phase of the award.

Special Note: To accommodate neurosurgeons, who need significant clinical activity to maintain their surgical skills, NINDS will accept 50% time commitment to the award.

Salary and Research Costs
For mentored (K99 phase) candidates in an extramural institution, NINDS will provide up to $50,000 per year for salary support, plus fringe, and up to $20,000 for research support costs. For those applicants that are clinicians (including those with M.D., D.D.S, D.V.M. and other licensed health professionals), NINDS will provide up to $95,000 per year for salary support. Budget details for mentored candidates in the NIH intramural program will be negotiated with the sponsoring laboratory and will be consistent with offers to scientists in comparable positions. The applicant should indicate a minimum of 9 person months effort for him/herself for the K99 phase. In the initial application, an itemized budget is not required for the R00 phase. At the time of transition to the R00 phase, the R00 applicant institution will submit a detailed budget for each budget period of the R00 project period that reflects the direct and indirect costs at the R00 applicant institution. Because institutions must offer a startup package for the R00 phase that at least equals the package one would get when hired into the same position without the R00 grant, awardees may draw a maximum of 30% salary from the R00 award, regardless of effort devoted specifically to the R00 project.

NINDS K99/R00 Pathway to Independence Award Recipients

See NIH Program Announcement: NIH Pathway to Independence Award (Parent K99/R00) (PA-16-193)

Important information about eligiblility for an NINDS K99/R00

See NOT-OD-15-052 which clarifies eligibility and budget information.

Notice of Clarification of Eligibility for K99/R00 Applications
https://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-153.html

Application Form SF 424

New Application Receipt Dates: February 12, June 12, October 12

Renewal, Resubmission, or Revised Application Dates: March 12, July 12, November 12

Program Contact:
Stephen J. Korn, Ph.D.
Director of Training and Workforce Development
301-496-4188; Fax 301-480-1080
korns@ninds.nih.gov

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Notices, Policy Announcements and Other Information

  • Notice of Support for Clinician-Scientists Supported by NINDS K08 and K23 Awards to Attend a Workshop (NOT-NS-13-028)
  • Discontinuation of Participation by NINDS in PA-11-196: Mentored Quantitative Research Development Award (K25) (NOT-NS-13-031)
  • Changes in Salary Caps for the K02, K08, and K23 Career Development Awards (NOT-NS-12-018)
  • Page Limits for Responsible Conduct of Research for K Awards (NOT-OD-11-059)
  • Requirements for Responsible Conduct of Research (NOT-OD-10-019)
  • Notice that NINDS Encourages Clinicians with Excellent Pre-residency Research Publication Records to Apply for Mentored Career Development (K08/K23) Awards without Waiting for Post-Residency Publications (NOT-NS-15-408)
  • Notice of Clarification of Eligibility for K99/R00 Applications (NOT-OD-15-153)
  • Modification of "No-Cost Extension" and "Carryover of Funds: Policies for the NIH Pathway to Independence Award (Parent K99/R00) (NOT-OD-16-092)
  • Additional Awardees Eligible for PA-16-288 "Research Supplements to Promote Diversity in Health-Related Research (Admin Supp)" (NOT-OD-16-110)

Citizenship Requirement: For all K awards, with the exception of the K99/R00 an individual must be a citizen or a non-citizen national of the United States or have been lawfully admitted for permanent residence at the time of award.  Please see specific announcement for information.

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