The purpose of this Notice is to inform the research community that the NIH Common Fund, along with its partner NIH Institutes, Centers, and Offices, is planning to issue a funding opportunity announcement (FOA) to support the NIH Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Program: FIRST Cohort. We expect to re-release this funding opportunity for a total of 3 rounds. This Notice is being provided to allow potential applicants sufficient time to develop meaningful plans for robust applications to this opportunity. The FOA is expected to be published in Fall, 2020 with an expected application due date in November 2020. This FOA will utilize the U54 activity code. Details of the planned FOA are provided below. Research Initiative Details The NIH supported biomedical research workforce is more likely to thrive in environments that support equity, diversity, and social justice. The overall program objective of Faculty Institutional Recruitment for Sustainable Transformation (FIRST) is to create cultures of inclusive excellence at NIH-funded institutions by implementing a set of well-integrated, evidence-based strategies and evaluating their impact on prespecified metrics of institutional culture, inclusion, and diversity. Inclusive excellence is a philosophical approach to higher education administration and processes that means attending to both the demographic diversity of faculty/students and the need for developing climates and cultures in institutions so that all have a chance to succeed in STEMM (National Academies of Sciences, Engineering, and Medicine 2019. The Science of Effective Mentorship in STEMM (STEMM stands for Science, Technology, Engineering, Mathematics, and Medicine)). The FIRST Program will provide one funding mechanism with opportunities for Highly Resourced Institutions (HRI) and Limited-Resourced Institutions (LRI) to apply independently or in a partnership arrangement to develop and implement faculty cohort models for the simultaneous hiring of a diverse group of research faculty. LRIs are institutions offering doctorate degrees in the health professions or in a health-related science and have a historical and current commitment to educating underrepresented students, and for institutions that deliver health care services, providing clinical services to medically underserved communities. They must also have received less than $50 million average in annual NIH funds within the three years prior to the time of application (applies Research Centers in Minority Institutions criteria ). Any individual who is competitive for a tenure track faculty position and who has demonstrated a strong commitment to promoting diversity and inclusive excellence is eligible for FIRST faculty positions. Faculty candidates will be required to submit a statement describing their commitment to promoting diversity and inclusive excellence. Institutions will decide how to evaluate this commitment, but some examples include the area of a candidate’s research program, active participation in diversity efforts, mentoring individuals from underrepresented backgrounds, volunteer activities in the community, etc. Selection for the program should be competitive and inclusion in the FIRST cohort will be viewed as a prestigious recognition of outstanding accomplishments both in scientific research and in promoting diversity and inclusive excellence. The program will support activities for faculty to receive multilevel mentoring, sponsorship, professional and research development embedded within institutions that are actively implementing integrated, systems-level approaches for sustainable culture change. FIRST applicant institutions are encouraged to enhance the diversity of the FIRST faculty cohort by including candidates from groups identified as underrepresented in the biomedical, clinical, behavioral, and social sciences, some of which are described in NOT-OD-20-031, such as racial and ethnic minorities, those from disadvantaged backgrounds, individuals with disabilities, and women at the faculty level. Institutional cohorts may be comprised of small clusters of scientists within several scientific areas, such as neuroscience, cardiovascular disease, cancer, minority health and health disparities, behavioral, social, or other research areas within the NIH mission either at one institution or at partnering institutions. FIRST Cohort programs will operationalize through three cores—Administrative, Faculty Development, and Evaluation cores. The overall goals and specific measurable objectives that the program expects to accomplish are in the areas of: sustainable institutional culture change; promote inclusive excellence by hiring a diverse cohort of new faculty; faculty development, mentoring, sponsorship, and promotion. Each institution will be responsible for evaluating its own FIRST program. The CEC will be responsible for evaluating the attainment of FIRST goals consortium wide.

Notice Change Key Dates PAR-18-657 Countermeasures Against Chemical Threats CounterACT) Research Centers Excellence U54 Clinical Trial Optional)". Notice Number: NOT-NS-20-086 Key Dates Release Date: July 10, 2020 Related Announcements PAR-18-657 - Countermeasures Against Chemical Threats CounterACT) Research Centers Excellence U54 Clinical Trial Optional) Issued National Institute Neurological Disorders Stroke NINDS) National Eye Institute NEI) National Institute Arthritis Musculoskeletal Skin Diseases NIAMS) National Institute Drug Abuse NIDA) National Institute Environmental Health Sciences NIEHS) Purpose purpose this notice to inform interested applicants a change the Key Dates PAR-18-657 "Countermeasures Against Chemical Threats CounterACT) Research Centers Excellence U54 Clinical Trial Optional)". September 9, 2020 receipt date been changed October 8, 2020. Changes show bold italics below. Currently Reads: Part 1. Overview Information Key Dates Application Due Date(s) September 11, 2018; September 10, 2019; September 9, 2020, 5:00 PM local time applicant organization. All types non-AIDS applications allowed this funding opportunity announcement due these dates. Applicants encouraged apply early allow adequate time make any corrections errors found the application during submission process the due date. Expiration Date September 10, 2020 Modified Read: Part 1. Overview Information Key Dates Application Due Date(s) September 11, 2018; September 10, 2019; October 8, 2020, 5:00 PM local time applicant organization. All types non-AIDS applications allowed this funding opportunity announcement due these dates. Applicants encouraged apply early allow adequate time make any corrections errors found the application during submission process the due date. Expiration Date October 9, 2020 other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: David A. Jett, Ph.D. National Institute Neurological Disorder Stroke NINDS) Telephone: 301-496-6035 Email: jettd@ninds.nih.gov

Notice Change Key Dates PAR-19-040 Countermeasures Against Chemical Threats CounterACT): Optimization Therapeutic Lead Compounds U01 Clinical Trial Optional)" Notice Number: NOT-NS-20-088 Key Dates Release Date: July 10, 2020 Related Announcements PAR-19-040 - Countermeasures Against Chemical Threats CounterACT): Optimization Therapeutic Lead Compounds U01 Clinical Trial Optional) Issued National Institute Neurological Disorders Stroke NINDS) National Eye Institute NEI) National Institute Arthritis Musculoskeletal Skin Diseases NIAMS) National Institute Drug Abuse NIDA) National Institute Environmental Health Sciences NIEHS) Purpose purpose this notice to inform interested applicants a change the Key Dates PAR-19-040 "Countermeasures Against Chemical Threats CounterACT): Optimization Therapeutic Lead Compounds U01 Clinical Trial Optional)". September 9, 2020 receipt date been changed October 8, 2020. Changes show bold italics below. Currently Reads: Part 1. Overview Information Key Dates Application Due Date(s) September 10, 2019; September 9, 2020; September 14, 2021, 5:00 PM local time applicant organization. All types non-AIDS applications allowed this funding opportunity announcement due these dates. Applicants encouraged apply early allow adequate time make any corrections errors found the application during submission process the due date. Modified Read: Part 1. Overview Information Key Dates Application Due Date(s) September 10, 2019; October 8, 2020; September 14, 2021, 5:00 PM local time applicant organization. All types non-AIDS applications allowed this funding opportunity announcement due these dates. Applicants encouraged apply early allow adequate time make any corrections errors found the application during submission process the due date. other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: David A. Jett, Ph.D. National Institute Neurological Disorder Stroke NINDS) Telephone: 301-496-6035  Email: jettd@ninds.nih.gov

Notice Change Key Dates RFA-NS-20-030 Research Program Award R35 Clinical Trial Optional)" Notice Number: NOT-NS-20-092 Key Dates Release Date: July 7, 2020 Related Announcements RFA-NS-20-030 - Research Program Award R35 Clinical Trial Optional) Issued National Institute Neurological Disorders Stroke NINDS) Purpose purpose this notice to inform interested applicants a change the Key Dates RFA-NS-20-030 "Research Program Award R35 Clinical Trial Optional)". July 31, 2020 receipt date been moved August 14, 2020. Changes shown below bold italics. Currently Reads: Part 1. Overview Information Key Dates Letter Intent Due Date(s) July 1, 2020 Application Due Date(s) July 31, 2020 late applications be accepted this Funding Opportunity Announcement. applications due 5:00 PM local time applicant organization. Alltypes non-AIDS applicationsallowed this funding opportunity announcement due the listed date(s). Applicants encouraged apply early allow adequate time make any corrections errors found the application during submission process the due date. Expiration Date August 01, 2020 Modified Read: Part 1. Overview Information Key Dates Letter Intent Due Date(s) July 21, 2020 Application Due Date(s) August 14, 2020 late applications be accepted this Funding Opportunity Announcement. applications due 5:00 PM local time applicant organization. Alltypes non-AIDS applicationsallowed this funding opportunity announcement due the listed date(s). Applicants encouraged apply early allow adequate time make any corrections errors found the application during submission process the due date. Expiration Date August 15, 2020 other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Anna Taylor, Ph.D.National Institute Neurological Disorders Stroke NINDS)Telephone: 301-827-3565Email:anna.taylor@nih.gov