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Fogarty Global Trauma and Injury Research Training Program (D43 Clinical Trial Optional)

RFA
Wednesday, February 17, 2021
Saturday, April 17, 2021
RFA-TW-21-003

Funding Opportunity Purpose

The overall objective of this Funding Opportunity Announcement (FOA) is to strengthen trauma and injury research capacity at academic institutions in low- and middle-income countries (LMICs) through support for research training programs.

Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Basic Experimental Studies with Humans Required)

PAR
Monday, February 1, 2021
Thursday, March 18, 2021
R01
PAR-21-144
David A. Jett

Funding Opportunity Purpose

This funding opportunity announcement (FOA) invites research projects that seek to explain the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in human health, illness, recovery, and overall wellbeing. Types of projects submitted under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical and/or behavioral outcomes in humans to understand fundamental aspects of phenomena related to social connectedness and isolatedness. NIH considers such studies as prospective basic science studies involving human participants that meet the NIH definition of basic research and fall within the NIH definition of clinical trials (see, e.g., NOT-OD-19-024) Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind.

Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Clinical Trials Not Allowed)

PAR
Monday, February 1, 2021
Thursday, March 18, 2021
R01
PAR-21-145
David A. Jett

Funding Opportunity Purpose

This funding opportunity announcement (FOA) invites research projects that seek to model the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in health, illness, recovery, and overall wellbeing. Both animal and human subjects research projects are welcome. Researchers proposing basic science experimental studies involving human participants should consider this FOAs companion for basic experimental studies with humans.

Digital Technologies to Address the Social Determinants of Health in Context of Substance Use Disorders (SUD) (R41/R42 Clinical Trial Optional)

RFA
Monday, January 11, 2021
Heal
Saturday, February 27, 2021
R41/R42
RFA-DA-21-031
Adam Hartman

HEAL Initiative: Optimizing Multi-Component Service Delivery Interventions for People with Opioid Use Disorder, Co-Occurring Conditions, and/or Suicide Risk (R01 Clinical Trials Optional)

RFA
Monday, January 11, 2021
Heal
Friday, March 19, 2021
R01
RFA-MH-21-145
Adam Hartman

Funding Opportunity Purpose

In April 2018, the National Institutes of Health (NIH) launched the HEAL (Helping to End Addiction Long-term) Initiative, an aggressive, trans-agency effort to speed scientific solutions to stem the national opioid public health crisis. In response to this initiative, the National Institute of Mental Health (NIMH), in partnership with other NIH Institutes, Centers, and Offices, invites research that will optimize multi-component service delivery interventions for people with opioid use disorder (OUD) and co-occurring conditions, to include mental disorders and/or suicide risk. The purpose of the initiative is to support studies that will (1) test the overall effectiveness of multi-component interventions for OUD and co-occurring conditions and (2) examine the relative contribution of constituent components to overall effectiveness. This research will streamline service packages so they only include components that drive clinical improvements for complex conditions. The content of this RFA complements research stemming from RFA-DA-21-029 and RFA-DA-21-030.

Digital Technologies to Address the Social Determinants of Health in Context of Substance Use Disorders (SUD) (R43/R44 Clinical Trial Optional)

RFA
Monday, January 11, 2021
Heal
Saturday, February 27, 2021
R43/R44
RFA-DA-21-032
Adam Hartman

Funding Opportunity Purpose

The purpose of this Funding Opportunity Announcement is to support research applications for commercializable, digital products that aim at positively affecting the fundamental social and environmental conditions that are risk factors for the populations affected by substance use/misuse or Substance Use Disorders (excluding Alcohol Use Disorder).

HEAL Initiative: HEALthy Brain and Child Development Consortium Administrative Core (U24 - Clinical Trial Not Allowed)

RFA
Monday, January 11, 2021
Thursday, April 1, 2021
U24
RFA-DA-21-022

Funding Opportunity Purpose

The NIH Helping to End Addiction Long-termSM (HEAL) Initiative and the National Institute on Drug Abuse (NIDA), the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Mental Health (NIMH), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the Eunice Kennedy Shriver Institute of Child Health and Human Development (NICHD), the Office of Behavioral and Social Sciences Research (OBSSR), the Office of Research on Womens Health (ORWH), the National Institute of Environmental Health Sciences (NIEHS), the National Institute on Minority Health and Health Disparities (NIMHD), and the Environmental influences on Child Health Outcomes (ECHO) Program, intend to jointly fund the HEALthy Brain and Child Development (HBCD) Study using the cooperative agreement award mechanism. This Funding Opportunity Announcement (FOA) solicits applications for the HBCD Consortium Administrative Core. This FOA runs in parallel with companion FOAs that solicit applications for a single Data Coordinating Center (RFA-DA-21-023) and multiple Research Project Sites (RFA-DA-21-020 and RFA-DA-21-021). It is expected that investigators, upon funding, will work jointly with NIH scientific staff to assist, guide, coordinate, or participate in project activities.

HEAL Initiative: HEALthy Brain and Child Development Data Coordinating Center (U24)

RFA
Monday, January 11, 2021
Thursday, April 1, 2021
U24
RFA-DA-21-023

Funding Opportunity Purpose

The NIH Helping to End Addiction Long-termSM (HEAL) Initiative and the National Institute on Drug Abuse (NIDA), the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Mental Health (NIMH), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the Eunice Kennedy Shriver Institute of Child Health and Human Development (NICHD), the Office of Behavioral and Social Sciences Research (OBSSR), the Office of Research on Womens Health (ORWH), the National Institute of Environmental Health Sciences (NIEHS), the National Institute on Minority Health and Health Disparities (NIMHD), and the Environmental influences on Child Health Outcomes (ECHO) Program, intend to jointly fund the HEALthy Brain and Child Development (HBCD) Study using the cooperative agreement award mechanism. This Funding Opportunity Announcement (FOA) solicits applications for a Data Coordinating Center. This FOA runs in parallel with companion FOAs that solicit applications for research project sites (RFA-DA-21-020 and RFA-DA-21-021) and a single Consortium Administrative Core (RFA-DA-21-022). It is expected that investigators, upon funding, will work jointly with NIH scientific staff to assist, guide, coordinate, or participate in project activities.

HEAL Initiative: HEALthy Brain and Child Development Study (Collaborative U01- Clinical Trial Not Allowed)

RFA
Monday, January 11, 2021
Thursday, April 1, 2021
U01
RFA-DA-21-020

Funding Opportunity Purpose

To address critical questions surrounding the long-term impact of substance exposure on child development, the NIH seeks to create a large, diverse cohort of pregnant women, who along with their offspring, will be followed for 10 years. The cohort will consist of mother and baby dyads recruited beginning in the 2nd trimester of pregnancy and through birth; and will include babies exposed pre- or perinatally to prescription and illicit opioids, marijuana, stimulants, alcohol and nicotine. A deep, nuanced understanding of factors that affect a childs health, brain, and behavioral development is expected to emerge from this study, which is an essential first step toward designing policies and interventions that promote well-being and resiliency in children. Applications are sought from qualified researchers with the capacity and expertise to recruit and retain vulnerable populations for studies that will include neuroimaging, cognitive and behavioral assessments along with collection and analysis of biospecimens from mom and baby.

HEAL Initiative: HEALthy Brain and Child Development Study (U01 - Clinical Trial Not Allowed)

RFA
Monday, January 11, 2021
Thursday, April 1, 2021
U01
RFA-DA-21-021

Funding Opportunity Purpose

The NIH Helping to End Addiction Long-termSM (HEAL) Initiative and the National Institute on Drug Abuse (NIDA), the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Mental Health (NIMH), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the Eunice Kennedy Shriver Institute of Child Health and Human Development (NICHD), the Office of Behavioral and Social Sciences Research (OBSSR), the Office of Research on Womens Health (ORWH), the National Institute of Environmental Health Sciences (NIEHS), and the National Institute on Minority Health and Health Disparities (NIMHD), intend to jointly fund the HEALthy Brain and Child Development (HBCD) Study using the cooperative agreement award mechanism. This Funding Opportunity Announcement (FOA) solicits applications for unlinked Research Project Sites. This FOA runs in parallel with companion FOAs that solicit applications for linked Research Project Sites (RFA-DA-21-020), a single Consortium Administrative Core (RFA-DA-21-022) and a single Data Coordinating Center (RFA-DA-21-023). It is expected that investigators, upon funding, will work jointly with NIH scientific staff to assist, guide, coordinate, or participate in project activities.

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