Striatonigral Degeneration Information Page

Striatonigral Degeneration Information Page


What research is being done?

The NINDS supports and conducts research on disorders of the brain and nervous system such as striatonigral degeneration. This research focuses on finding ways to prevent and treat these disorders.

Information from the National Library of Medicine’s MedlinePlus
Degenerative Nerve System

×
What research is being done?

The NINDS supports and conducts research on disorders of the brain and nervous system such as striatonigral degeneration. This research focuses on finding ways to prevent and treat these disorders.

Information from the National Library of Medicine’s MedlinePlus
Degenerative Nerve System

The NINDS supports and conducts research on disorders of the brain and nervous system such as striatonigral degeneration. This research focuses on finding ways to prevent and treat these disorders.

Information from the National Library of Medicine’s MedlinePlus
Degenerative Nerve System

Search Disorders

Definition
Definition
Treatment
Treatment
Prognosis
Prognosis
Clinical Trials
Clinical Trials
Organizations
Organizations
Publications
Publications
Definition
Definition

Striatonigral degeneration is a neurological disorder caused by a disruption in the connection between two areas of the brain-the striatum and the substantia nigra. These two areas work together to enable balance and movement. Striatonigral degeneration is a type of multiple system atrophy (MSA). Symptoms of the disorder resemble some of those seen in Parkinson's disease, including rigidity, instability, impaired speech, and slow movements.

×
Definition

Striatonigral degeneration is a neurological disorder caused by a disruption in the connection between two areas of the brain-the striatum and the substantia nigra. These two areas work together to enable balance and movement. Striatonigral degeneration is a type of multiple system atrophy (MSA). Symptoms of the disorder resemble some of those seen in Parkinson's disease, including rigidity, instability, impaired speech, and slow movements.

Treatment
Treatment

There is no cure for striatonigral degeneration, and treatments for the disorder have variable success. Treatments used for Parkinson's disease are recommended. However, unlike Parkinson's disease, striatonigral degeneration is not responsive to levodopa. Dopamine and anticholinergics provide some benefit. Generally, treatment is reevaluated as the disorder progresses.

×
Treatment

There is no cure for striatonigral degeneration, and treatments for the disorder have variable success. Treatments used for Parkinson's disease are recommended. However, unlike Parkinson's disease, striatonigral degeneration is not responsive to levodopa. Dopamine and anticholinergics provide some benefit. Generally, treatment is reevaluated as the disorder progresses.

Definition
Definition

Striatonigral degeneration is a neurological disorder caused by a disruption in the connection between two areas of the brain-the striatum and the substantia nigra. These two areas work together to enable balance and movement. Striatonigral degeneration is a type of multiple system atrophy (MSA). Symptoms of the disorder resemble some of those seen in Parkinson's disease, including rigidity, instability, impaired speech, and slow movements.

Treatment
Treatment

There is no cure for striatonigral degeneration, and treatments for the disorder have variable success. Treatments used for Parkinson's disease are recommended. However, unlike Parkinson's disease, striatonigral degeneration is not responsive to levodopa. Dopamine and anticholinergics provide some benefit. Generally, treatment is reevaluated as the disorder progresses.

Prognosis
Prognosis

Striatonigral degeneration progresses slowly. Some patients have normal life expectancy.

×

Striatonigral degeneration progresses slowly. Some patients have normal life expectancy.

Prognosis
Prognosis

Striatonigral degeneration progresses slowly. Some patients have normal life expectancy.

Definition

Striatonigral degeneration is a neurological disorder caused by a disruption in the connection between two areas of the brain-the striatum and the substantia nigra. These two areas work together to enable balance and movement. Striatonigral degeneration is a type of multiple system atrophy (MSA). Symptoms of the disorder resemble some of those seen in Parkinson's disease, including rigidity, instability, impaired speech, and slow movements.

Treatment

There is no cure for striatonigral degeneration, and treatments for the disorder have variable success. Treatments used for Parkinson's disease are recommended. However, unlike Parkinson's disease, striatonigral degeneration is not responsive to levodopa. Dopamine and anticholinergics provide some benefit. Generally, treatment is reevaluated as the disorder progresses.

Prognosis

Striatonigral degeneration progresses slowly. Some patients have normal life expectancy.

What research is being done?

The NINDS supports and conducts research on disorders of the brain and nervous system such as striatonigral degeneration. This research focuses on finding ways to prevent and treat these disorders.

Information from the National Library of Medicine’s MedlinePlus
Degenerative Nerve System

Patient Organizations
American Parkinson Disease Association
135 Parkinson Avenue
Staten Island
NY
Staten Island, NY 10305-1425
Tel: 718-981-8001; 800-223-2732; 877-223-3801 (Young Onset Center)
National Parkinson Foundation
200 SE 1st Street
Suite 800
Miami
FL
Miami, FL 33137
Tel: 800-473-4636
Parkinson's Action Network (PAN)
Grand Central Station, P.O. Box 4777
New York City
NY
New York City, NY 10063-4777
Tel: 800-708-7644
Parkinson's Disease Foundation (PDF)
1359 Broadway
Suite 1509
New York
NY
New York, NY 10018
Tel: 212-923-4700; 800-457-6676
The Multiple System Atrophy Coalition
9935-D Rea Road
Charlotte
NC
Charlotte, NC 28227
Tel: 866-737-5999
Patient Organizations