2012 NINDS Udall Centers Meeting Agenda

2012 NINDS Udall Centers Meeting Agenda

14th Annual Udall Center Directors' Meeting
October 1-3, 2012
Washington Plaza Hotel
Washington, DC

Summary  Participant List  Executive Summary

Monday October 1, 2012. Udall Center Clinical Cores Meeting

Time Meeting Item
11:00 a.m. NINDS Data Management Resource (DMR) for Parkinson’s Disease Research. Margaret L. Sutherland, Ph.D./ NINDS, NIH
11:20 a.m. Discussion
  Overview of Udall Center Clinical Cores
11:30 a.m. Robert E. Burke, M.D./Columbia University
11:50 a.m. Andrew Feigin, M.D./Feinstein Institute for Medical Research
12:10 p.m. Susan S. Bassett, Ph.D./Johns Hopkins University School of Medicine
12:30 p.m. William K. Scott, M.D./University of Miami
12:50 p.m. Working Lunch
1:20 p.m. Zbigniew K. Wszolek, M.D./The Mayo Clinic Jacksonville
1:40 p.m. Rachel Gross, M.D./University of Pennsylvania
2:00 p.m. James Leverenz, M.D./University of Washington
2:20 p.m. BREAK
  Focused Discussion: Collaborative Opportunities
2:45 p.m. Genetics studies in Udall Center cohorts. Moderator: Jeffery M. Vance, M.D., Ph.D./Director, University of Miami Udall Center
3:30 p.m. Cognitive decline and Parkinson’s disease with dementia (PDD): studies in Udall Center cohorts. Moderator: John Q. Trojanowski, M.D., Ph.D./Director, University of Pennsylvania Udall Center
4:15 p.m. Harmonization of clinical measures and standardization of data collection across Udall Center cohorts. Moderator: Thomas J. Montine, M.D., Ph.D., Director, Pacific Northwest Udall Center
5:00 p.m. Discussion: Identification of next steps
5:30 p.m. Adjournment

Tuesday October 2, 2012. Udall Center Directors' Meeting

Time Meeting Item
8:00 a.m. Registration
8:30 a.m. Opening Remarks/NINDS Update. Story C. Landis, Ph.D./ Director, NINDS, NIH
9:00 a.m. Welcome

Robert E. Burke, M.D., 2012 Chair, Udall Center Coordinating Committee (UC3), Director, Columbia University Udall Center

Beth‐Anne Sieber, Ph.D., Program Director, NINDS, NIH

  Cross-cutting Discussion Topics
9:30 a.m. The PINK1‐Parkin Connection

Introduction. Robert E. Burke, M.D./Director, Columbia University Udall Center

Do PINK1 and Parkin promote mitochondrial turnover in neurons?. Leo J. Pallanck, Ph.D./University of Washington

Therapeutic strategies to mitigate mitochondrial dysfunction in Parkinson’s disease and beyond. Richard Youle, Ph.D./NINDS, NIH

The regulation of mitochondrial movement in neurons. Thomas L Schwarz, Ph.D./Harvard Medical School

Discussion

11:30 a.m. Lunch Presentation

Biomedical research: a congressional update. Amy Comstock Rick, Esq./Chief Executive Officer, Parkinson’s Action Network

11:30 a.m. Udall Center Administrators’ Lunch Meeting. Janice Savage, M.S./Columbia University
12:30 p.m. Beyond the basal ganglia: the role of thalamus, cerebellum, and cortex in the pathophysiology of Parkinson’s disease

Introduction. Thomas Wichmann, M.D., Ph.D./Director, Emory University Udall Center

The thalamus in Parkinson’s disease. Yoland Smith, Ph.D./Emory University

Thalamocortical dysfunction in Parkinson’s disease. Robert S. Turner, Ph.D./University of Pittsburgh

Basal ganglia loops with the cerebral cortex and cerebellum. Peter L. Strick, Ph.D./University of Pittsburgh

Discussion

2:30 p.m. BREAK
3:00 p.m. New insights on the genetics of Parkinson’s disease

Introduction. Dennis W. Dickson, M.D., Ph.D./Director, Mayo Clinic Jacksonville Udall Center

Next generation methods to discover new PD genes. Andrew Singleton, Ph.D./National Institute on Aging, NIH

Mega meta analyses of clinical PD GWAS and the NeuroChip Initiative. Tatiana Foroud, Ph.D./Indiana University

Autopsy‐verified PD GWAS: emerging results. Jeffery M. Vance, M.D., Ph.D./Director, University of Miami Udall Center

5:00 p.m. Poster Session and Judging
6:30 p.m. NINDS–NGOs Meeting

Wednesday October 3, 2012. Udall Center Updates: Significant Advances

Time Meeting Item
8:30 a.m. A new model of Parkinson’s disease based on transmission of pathological alpha‐synuclein. Virginia M.‐Y. Lee, Ph.D., M.B.A./University of Pennsylvania Udall Center
9:00 a.m. Toward understanding PD pathogenesis and how to stop progression. D. James Surmeier, Ph.D./Director, Northwestern University Udall Center
9:30 a.m. Mitochondrial biogenesis: The rest of the story. Ted M. Dawson, M.D., Ph.D./Director, Johns Hopkins University Udall Center
10:00 a.m. Axon regeneration by mTor signaling: neurorestoration for Parkinson’s disease. Robert E. Burke, M.D./Director, Columbia University Udall Center
10:30 a.m. BREAK
11:00 a.m. Synaptic remodeling in the parkinsonian striatum: impact of age and levodopa. Timothy Collier, Ph.D./Director, Michigan State University Udall Center
11:30 a.m. Abnormal network activity in prodromal Parkinson’s disease. David Eidelberg, M.D./Director, Feinstein Institute for Medical Research Udall Center
12:00 p.m. Pacific Northwest Udall Center: Updates on cognitive impairment in PD. Thomas J. Montine, M.D., Ph.D./Director, Pacific Northwest Udall Center (PANUC) at the University of Washington
12:30 p.m. Rare variants in Parkinson’s disease. Jeffery M. Vance, M.D., Ph.D./Director, University of Miami Udall Center
1:00 p.m. Closing Remarks

Story Landis, Ph.D./Director, NINDS, NIH

Thomas J. Montine, M.D., Ph.D./2013 Chair, Udall Center Coordinating Committee (UC3), Director, Pacific Northwest Udall Center (PANUC)

1:15 p.m. Adjournment (Udall investigators and guests)
1:15 p.m. Udall Center Coordinating Committee (UC3) Meeting
2:00 p.m. NINDS Udall Center Directors' Meeting Adjournment