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Traumatic Brain Injury Research (TBI)


Program Contact for TBI Research

Patrick SF Bellgowan, Ph.D.
Program Director
NINDS TBI Program
psfb@mail.nih.gov
Joanna Vivalda, R.N., M.B.A.
Clinical Trial Specialist
Clinical Research
joanna.vivalda@nih.gov
Neuroimaging is one of many tools used to investigate TBI.
Neuroimaging is one of many tools used to investigate TBI.
NINDS supports research on traumatic brain injury (TBI) to advance knowledge on mechanisms of injury and recovery, and to develop better diagnostic tools and more effective treatments. This website provides information on NINDS activities, opportunities and resources for TBI research. 
Dr. Walter Koroshetz, Director of NINDS, discusses TBI and the research progress in TBI through data sharing
Dr. Walter Koroshetz, Director of NINDS

Dr. Walter Koroshetz, Director of NINDS, discusses TBI and the research progress in TBI through data sharing.

To receive regular updates on funding announcements and other opportunities, please join the NINDS TBI Research Listserv.

NIH RePORTER, an online reporting tool, allows users to search a repository of NIH-funded TBI research projects and access publications and patents resulting from NIH funding. Please visit NINDS TBI for more general information.

Listen to TBI investigators discuss data sharing through the FITBIR Informatics System to accelerate TBI research progress on NIHNINDS YouTube.

New icon Researchers seek definition of chronic traumatic encephalopathy (pdf, 504 kb)

New icon Pre-Clinical Common Data Elements Table (pdf, 39 kb), Worksheet (pdf, 323 kb) and Publication (pdf, 290 kb) are now available.




Common Data Elements

Common Data Elements (CDE) logo

NINDS CDEs for TBI

Common Data Elements enable clinical investigators to systemically collect, analyze and share data across the research community.  

NINDS has developed common data elements for TBI.

The International Common Data Elements Project – Getting Further, Faster

Pre-Clinical Common Data Elements now available:

FITBIR Informatics System

Federal Interagency Traumatic Brain Injury Research (FITBIR) Informatics System logo

FITBIR Informatics System
FITBIR Informatics System Data Sharing Policy
 

Dr. Mona Hicks of One Mind and COL Dallas Hack of the Department of Defense discuss data sharing for the TBI community by creating the FITBIR Informatics System and discussing its value for TBI research progress.
Dr. Mona Hicks and COL Dallas Hack

Dr. Mona Hicks of One Mind and COL Dallas Hack of the Department of Defense discuss data sharing for the TBI community by creating the FITBIR Informatics System and discussing its value for TBI research progress.

The Federal Interagency TBI Research (FITBIR) Informatics System is a platform, developed by the NIH and the Department of Defense, which allows data sharing across the entire TBI community.

Sharing data, associated tools and methodologies accelerates research progress by allowing re-analysis of data, as well as re-aggregation, integration and rigorous comparison with other data, tools and methods. 

 

Clinical Research


Dr. Geoffrey Manley of the University of California San Francisco discusses the value of TBI data sharing and comparative effective research in his TRACK-TBI initiative.
Dr. Geoffrey Manley
University of California San Francisco

Dr. Geoffrey Manley of the University of California San Francisco discusses the value of TBI data sharing and comparative effective research in his TRACK-TBI initiative.
NINDS supports clinical research and clinical trials to advance the understanding and treatment of TBI.

Recent NINDS-sponsored clinical research in TBI include:

The Neurological Emergencies Treatment Trials (NETT) Network engages clinicians and providers at the front lines of emergency care to conduct multicenter clinical trials focused on improving outcomes in patients with TBI and acute neurological injuries. Please consult the NINDS Office of Clinical Research website for further information.

To learn more about these trials and others, please search  ClinicalTrials.gov.

Translational Research

Office of Translational Research chart
NINDS Office of Translational Research

NINDS Translational Program focuses on preclinical development and testing of novel therapeutics and devices.

Examples of TBI projects funded under this cooperative program include:

Workshops & Meetings

Neurological Effects of Blast Injury cover image
 

International TBI Research (InTBIR)

The International Initiative for TBI Research (InTBIR) is a collaborative effort of the NIH, the European Commission and the Canadian Institutes of Health to advance clinical TBI research, treatment and care. 

 

Last Modified January 22, 2016