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Molecular Neuropharmacology Section - Division of Intramural Research



2014

Xiao, J., Free, R.B., Barnaeva, E., Conroy, J.L., Doyle, T.B., Miller, B., Bryant-Genevier, M., Taylor, M.K., Hu. X., Dulcey, A. E., Southall, N., Ferrer, M., Titus, S., Zheng, Z., Sibley, D.R., and Marugan, J.J.
Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists, Journal of Medicinal Chemistry, 2014 Full Text/Abstract

Free, R.B., Chun, L.S., Moritz, A.E., Miller, B., Doyle, T.B., Conroy, J.L., Padron, Meade, J.A., Xiao, J., Hu, X., Dulcey, A.E., Han, Y., Duan, L., Titus, Bryant-Genevier, M., Barnaeva, E., Ferrer, M., Javitch, J.J., Beuming, T., Shi, L., Southall, N., Marugan, J.J., and Sibley, D.R.
Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor, Molecular Pharmacology, 2014

2013

Chun, L.S., Free, R.B., Doyle, T.B., Huang, X.-P., Rankin, M.L., and Sibley, D.R.
D1-D2 dopamine receptor synergy promotes calcium signaling via multiple mechanisms, Molecular Pharmacology, 2013, vol. 84:, pp. 190-200. Full Text/Abstract

Bergman, J., Roof, R.A., Furman, C.A., Conroy, J.L., Mello, N.K., Sibley, D.R., and Skolnick, P.,
Modification cocaine self-administration by buspirone (Buspar®): potential involvment of D3 and D4 dopamine receptors, International Journal of Neuropsychopharmacology, 2013, vol. 16:, pp. 445-458. Full Text/Abstract

2012

Newman, A.H., Blaylock, B.L., Nader, M.A., Bergman, J., Sibley, D.R., Skolnick, P.,
Medication Discovery for Addiction: Translating the Dopamine D3 Receptor Hypothesis, Biochemical Pharmacology,, 2012, vol. 84:, pp. 882-890,. Full Text/Abstract

Maison, S.F., Liu, X.-P., Eatock, R.A., Sibley, D.R., Grandy, D.K., and Liberman, M.C.,
Dopaminergic signaling in the cochlea: receptor expression patterns and deletion phenotypes,, Journal of Neuroscience,, 2012, vol. 32:, pp. 344-355,. Full Text/Abstract

2011

Reichart, D.L., Hinkle, R.T., Lefever, F.R., Dolan, E.T., Dietrich, J.A., Sibley, D.R., and Isfort, R.J.,
Activation of the dopamine D1 receptor increases skeletal muscle mass and force production,, BMC Musculoskeletal Disorders, 2011, vol. 12:, pp. 27-35,. Full Text/Abstract

Skinberb, M., Sibley, D.R., Javitch, J.A., and Abi-Dargham, A.,
Imaging the High Affinity State of the Dopamine D2 Receptor: fact or fiction,, Biochemical Pharmacology,, 2011, vol. 83:, pp. 193-198,. Full Text/Abstract

Kramer, P.F., Christensen, C.H., Hazelwood, L.A., Bobi, A., Bock, R., Sibley, D.R., Mateo, Y., Alvarez, V.A.,
Dopamine D2 receptor over-expression alters behavior and physiology in Drd2-GFP mice,, Journal of Neuroscience,, 2011, vol. 31:, pp. 126-132,. Full Text/Abstract

Asico, L., Zhang, X. Jiang, J. Cabrera, D. Escano, C. Sibley, D.R. Wang, X. Yang, Y., Mannon, R. Jones, J. Armando, I. Jose, P.A.,
Lack of renal dopamine D5 receptors promotes hypertension,, Journal of the American Society of Nephrology, 2011, vol. 22:, pp. 82-89. Full Text/Abstract

Banala, A.K., Levy, B.A., Khatri, S.S., Furman, C.A., Roof, R.A., Mishra, Y., Griffin, S.A., Sibley, D.R., Luedtke, R.R., Hauk-Newman, A.,
N-(3-Fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl) piperazine-1-yl)-butyl)-aryl carboxamides as Selective Dopamine D3 Receptor Ligands: Critical Role of the Carboxamide Linker for D3 Receptor Selectivity, Journal of Medicinal Chemistry, 2011, vol. 54:, pp. 3581-3594,. Full Text/Abstract

2010

Rankin, M.L., and Sibley, D.R.
Consitutive phosphorylation by protein kinase C regulates D1 dopamine receptor signaling, Journal of Neurochemistry, 2010, vol. 115, pp. 1655-1667. Full Text/Abstract

Skinberg, M., Liow, J.-S., Seneca, N., Hong, J., Lu, S., Thorsell, A., Heilig, M., Pike, V.W., Halldin, V., Sibley, D.R., and Innis, R.B.
Dopamine D2 receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-defective mouse model, Neuroimage, 2010, vol. 50, pp. 1402-1407. Full Text/Abstract

Skinbjerb, M., Seneca, N., Liow, J.-S., Hong, J., Weinschenker, D., Pike, V.W., Halldin, C., Sibley, D.R., and Innis, R.B.
Dopamine-β-hydroxylase deficient mice have normal densities of D2 dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding data, Synapse, 2010, vol. 64, pp. 699-703. Full Text/Abstract

Wang, X., Luo, Y., Escano, C.S., Yang, Z., Asico, L., Li, H., Jones, J.E., Armando, I., Lu, Q., Sibley, D.R., Eisner, G.M., Jose, P.A.
Upregulation of renal sodium transporters in D5 dopamine receptor deficient mice, Hypertension, 2010, vol. 55, pp. 1431-1437. Full Text/Abstract

Rex, E., Rankin, M.L., Yang, Y., Lu, Q., Gerfen, C.R., and Sibley, D.R.
Identification of RanBP9/10 as interacting partners for protein kinase Cs γ/δ and the D1 dopamine receptor: regulation of PKC-mediated receptor phosphorylation, Molecular Pharmacology, 2010, vol. 78, pp. 69-80. Full Text/Abstract

2009

Free RB, Hazelwood LA, Sibley DR.
Identifying novel protein-protein interactions using co-immunoprecipitation and mass spectroscopy., Curr Protoc Neurosci., 2009, vol. Chapter 5, pp. Unit 5.28. Full Text/Abstract

Namkung, Y., Dipace, C., Javitch, J.A., and Sibley, D.R.
G protein-coupled receptor kinase-mediated phosphorylation mediates post-endocytic trafficking of the D2 dopamine receptor, Journal of Biological Chemistry, 2009, vol. 284, pp. 15038-15051. Full Text/Abstract

Sahu, A., Tyeryar, K.R., Vongtau, H.O., Sibley, D.R., and Undie, A.S.
D5 dopamine receptors are required for dopaminergic activation of phospholipase C, Molecular Pharmacology, 2009, vol. 75, pp. 447-453. Full Text/Abstract

Skinbjerb, M., Ariano, M.A., Thorsell, A., Heilig, M., Halldin, C., Innis, R.B., and Sibley, D.R.
Arrestin3 mediates D2 Dopamine receptor internalization, Synapse, 2009, vol. 63, pp. 621-624. Full Text/Abstract

Namkung, Y., Dipace, C., Urizar, U., Javitch, J.A., and Sibley, D.R.
G protein-coupled receptor kinase-2 constitutively regulates D2 receptor expression and signaling independent of receptor phosphorylation, Journal of Biological Chemistry, 2009, vol. 284, pp. 34103-34115. Full Text/Abstract

Skinbjerb, M., Namkung, Y., Halldin, C., Innis, R.B., and Sibley, D.R.
Pharmacological characterization of 2-methoxy-N-propylnorapomorphine’s (MNPA) interactions with D2 and D3 dopamine receptors, Synapse, 2009, vol. 63, pp. 462-475. Full Text/Abstract

2008

Hazelwood, L.A., Free, B.F., Cabrera, D.M., Skinbjerb, M., and Sibley, D.R.
Reciprocal modulation of function between the D1 and D2 dopamine receptors and the Na+, K+-ATPase, Journal of Biological Chemistry, 2008, vol. 283, pp. 36441-36453. Full Text/Abstract

Li, H. Armando, I., Yu, P., Escano, C., Mueller, S., Asico, L., Pascua, A., Lu, Q., Villar, V., Jones, J., Periasamy, A., Creswell, K., Guillemette, G., Sibley, D.R., Felder, R., Jose, P.A.
Dopamine D5 receptors mediate AT1 angiotensin receptor degradation via ubiquitin-proteosome pathway, Journal of Clinical Investigation, 2008, vol. 118, pp. 2180-2189. Full Text/Abstract

Seneca, N., Skinbjerb, M., Zoghbi, S.S., Liow, J.-S., Hong, J., Gladding, R.L., Hong, J., Kannan, P., Tuan, E., Sibley, D.R., Haldin, C., Pike, V.W., Innis, R.B
Kinetic brain analysis and whole-body imaging in monkey of [11C]MNPA, a dopamine agonist radioligand, Synapse, 2008, vol. 62, pp. 700-709. Full Text/Abstract

Seneca, N., Zoghbi, S.S., Skinbjerb, M., Liow, J.-S., Hong, J., Sibley, D.R., Pike, V.W., Haldin, C., Innis, R.B.
Occupancy of Brain D2/3 Receptors in Rat Brain by Endogenous Dopamine Measured with the Agonist Positron Emission Tomography Radioligand [11, Synapse, 2008, vol. 65, pp. 756-763. Full Text/Abstract

O�Sullivan, G., Dunleavy, M., Hakansson, K., Kinsella, A., Croke, D.T., Fienberg, A.A., Greengard, P., Sibley, D.R., Fisone, G., Henshall, D.C., and Waddington, J.L.
Dopamine D1 vs D5 Receptor-Dependent Induction of Seizures Involves DARPP-32 and ERK1/2 Signalling, Neuropharmacology, 2008, vol. 54, pp. 1051-1061. Full Text/Abstract

Rex, E.B., Rankin, M.L., Ariano, M.A., and Sibley, D.R.
Ethanol Regulation of D1 Dopamine Receptor Signaling is Mediated by Protein Kinase C in an Isozyme-Specific Fashion, Neuropsychopharmacology, 2008, vol. 32, pp. 2900-2911. Full Text/Abstract

Argilli, E., Sibley, D.R., Malenka, R.C., England, R.C., England, P.M., and Bonci, A.
Mechanism and time course of cocaine-induced LTP in the VTA, Journal of Neuroscience, 2008, vol. 28, pp. 9092-9100. Full Text/Abstract

Karlsson, R.M., Hefner, K.R., Sibley, D.R., and Holmes, A.
Comparison of dopamine D1 and D5 receptor knockout mice for cocaine locomotor sensitization, Psychopharmacology, 2008, vol. 100, pp. 117-127. Full Text/Abstract

Kim, O.J., Ariano, M.A., Namkung, Y., Marinec, P., Kim, E., Han, J., and David R. Sibley
D2 dopamine receptor expression and trafficking is regulated through direct interactions with ZIP, Journal of Neurochemistry, 2008, vol. 106, pp. 83-95. Full Text/Abstract

2007

Hernandez-Echeagaray, E., Cepeda, C., Ariano, M.A., Lobo, M.K., Sibley, D.R., and Levine, M.S.
Dopamine Reduction of GABA Currents in Medium-sized Spiny Neurons is Principally Mediated by the D1 Receptor Subtype, Neurochemical Research, 2007, vol. 32, pp. 229-240. Full Text/Abstract

Wang, Z., Armando, I., Asico, L.D., Escano, C., Wang, X., Felder, R.A., Schnackenberg, C.G., Sibley, D.R., Robillard, J.E., Eisner, G.M., and Jose, P.A.
The Elevated Blood Pressure of Human GRK4γ A142V Transgenic Mice is not Associated with Increased ROS Production, American Journal of Physiology, 2007, vol. 292(5), pp. H2083-2092. Full Text/Abstract

Free, R.B., Hazelwood, L.A., Namkung, Y., Cabrera, D.M., Spalding, H.N., Rankin, M.L., and Sibley, D.R.,
D1 and D2 Dopamine Receptor Expression is Regulated by Direct Interaction with the Chaperone Protein Calnexin, Journal of Biological Chemistry, 2007, vol. 282, pp. 2185-21300. Full Text/Abstract

2006

Tomiyama, K., Makihara, Y., Yamamoto, H., O’Sullivan, G., Nally, R.E., Tighe, O., Kinsella, A., Fienberg, A.A., Grandy, D.K., Greengard, P., Low, M.J., Rubinstein, M., Sibley, D.R., Croke, D.T., Koshikawa, N., and Waddington, J.L.
Disruption of orofacial movement topographies in congenic mutants with dopamine D5 but not D4 or DARPP-32 �knockout�, European Neuropsychopharmacology, 2006, vol. 16, pp. 437-445. Full Text/Abstract

Yang, Z., Asico, L.D., Yu, P., Wang, Z., Jones, J.E., Escano, C.S., Quinn, M.T., Sibley, D.R., Romero, G.G., Felder, R.A., and Jose, P.A.
D5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure in mice, American Journal of Physiology, 2006, vol. 290(1), pp. R96-R104. Full Text/Abstract

Rankin, M.L., Marinec, P.S., Cabrera, D.M., and Sibley, D.R.
The D1 Dopamine Receptor is Constitutively Phosphorylated by G Protein Coupled Receptor Kinase 4: evidence for a novel mechanism of regulation, Molecular Pharmacology, 2006, vol. 69, pp. 759-769 (see "Perspectives" article in same issue). Full Text/Abstract

2005

Sullivan, G.J., Kinsella, A., Sibley, D.R., Tighe, O., Croke, D.T., and Waddington, J.L.
Ethological Rsolution of Behavioral Topography and D1-like vs D2-like Agonist Responses in Congenic Dopamine D5 Receptor Mutants: Identification of D5:D2-like Interactions, Synapse, 2005, vol. 55, pp. 201-211. Full Text/Abstract

Yang, Z., Asico, L.D., Yu, P., Wang, Z., Jones, J.E., Bai, R., Sibley, D.R., Felder, R.A., and Jose, P.A.
D5 Dopamine Receptor Regulation of Phospholipase D, American Journal of Physiology, 2005, vol. 288(1), pp. H55-61. Full Text/Abstract

Zeng, C., Yang, Z., Jones, J. Wang, X., Altea, J., Mangrum, A.J., Hopfer, U., Sibley, D.R., Eisner, G.M., Felder, R.A., and Jose, P.A.
Interaction of AT1 and D5 dopamine receptors in renal proximal tubule cells, Hypertension, 2005, vol. 45, pp. 804-810. Full Text/Abstract

Kudwa, A.E., Dominguez-Salazar, E., Cabrera, D.M., Sibley, D.R. and Rissman, E.F.
Dopamine D5 Receptor Modulates Male and Female Sexual Behavior in Mice, Psychopharmacology, 2005, vol. 180, pp. 206-214. Full Text/Abstract

2004

Laplante, F., Sibley, D.R. and Quirion, R.
Reduction in Acetylcholine Release in the Hippocampus of Dopamine D5 Receptor Deficient Mice, Neuropsychopharmacology, 2004, vol. 29, pp. 1620-1629. Full Text/Abstract

Kim, O.-J., Gardner, B.R., Williams, D.B., Marinec, P.S., Cabrera, D.M., Peters, J.D., Mak, C.C., Kim, K.-M. and Sibley, D.R.
The Role of Phosphorylation in D1 Dopamine Receptor Desensitization: Evidence for a Novel Mechanism of Arrestin Association, Journal of Biological Chemistry, 2004, vol. 279, pp. 7999-8010. Full Text/Abstract

Yang, Z., Sibley, D.R., and Jose, P.A.
D5 Dopamine Receptor Knockout Mice and Hypertension, Journal of Receptors and Signal Transduction, 2004, vol. 24, pp. 149-164. Full Text/Abstract

O'Sullivan, G.J., Clifford, J.J., Tomiyama, K., Koshikawa, N., Drago, J., Sibley, D.R., Croke, D.T., an Waddington, J.L.
D1-like Dopamine Receptor-Mediated Function in Congenic Mouse Mutants with D1 versus D5 Receptor Knockout, Journal of Receptors and Signal Transduction, 2004, vol. 24, pp. 107-116. Full Text/Abstract

Homes, A., Lachowicz, J.E. and Sibley, D.R.
Dopamine Receptor Knockout Mice Reveal New Insights into Receptor Function and Pharmacology, Neuropharmacology, 2004, vol. 47/8, pp. 1117-1134. Full Text/Abstract

Namkung, Y. and Sibley, D.R.
Protein Kinase C Mediates Phosphorylation, Desensitization and Trafficking of the D2 Dopamine Receptor, Journal of Biological Chemistry, 2004, vol. 279, pp. 49533-49541. Full Text/Abstract

2003

Schetz, J.A., Kim, O.J., Sibley, D.R.
Pharmacological Characterization of Mammalian D1 and D2 Dopamine Receptors Expressed in Drosophila Schneider-2 Cells, Journal of Receptors and Signal Transduction, 2003, vol. 23, pp. 99-109. Full Text/Abstract

Lachowicz, J.E. and Sibley, D.R.
Dopaminergic Receptor Function Defined by Studying Genetically Alterered Mice, In Dopamine Receptors and Transporters, 2003, pp. pp 295-320.

Elliot, E.E., Sibley, D.R., and Katz, J.L.
Behavioral Effects of Cocaine in Dopamine D5 Receptor Knockout Mice, Psychopharmacology, 2003, vol. 169, pp. 161-168. Full Text/Abstract

Shapiro, D.A., Renock, S., Arington, E., Chiodo, L.A., Sibley, D.R., Roth, B.L., and Mailman, R.,
Aripiprazole, a Novel Atypical Antipsychotic with a Unique and Robust Pharmacology, Neuropsychopharmacology, 2003, vol. 28, pp. 1400-1411. Full Text/Abstract

2002

Sibley, D.R., Gardner, B, Peters, J.D., and Kim, O.-J.
Structural Insights into D1 Dopamine Receptor Phosphorylation and Desensitization, In Catecholamine Research: From Molecular Insights to Clinical Medicine, 2002, pp. pp 159-162.

Hollon, T.R., Bek, M.J., Lachowicz, J.E., Ariano, M.A., Mezey, E., Ramachandran, R., Wersinger, S.R., Soares-da-Silva, P., Liu, Z.F., Grinberg, A., Drago, J., Young, W.S., III, Westphal, H., Jose, P.A., and Sibley, D.R.
Mice Lacking D5 Dopamine Receptors Have Increased Sympathetic Tone and Are Hypertensive, The Journal of Neuroscience, 2002, vol. 22, pp. 10801-10810. Full Text/Abstract

Ariano, M.A., Aronin, N., DiFiglia, M., Tagle, D.A., Sibley, D.R., Leavitt, B.R., Hayden, M.R. and Levine, M.S.
Striatal Neurochemical Changes in Transgenic Models of Huntington's Disease, Journal of Neuroscience Research, 2002, vol. 68, pp. 716-729. Full Text/Abstract

Kim, O.J., Ariano, M.A., Lazzarini, R.A., Levine, M.S., and Sibley, D.R
Neurofilament-M Interacts with the D1 Dopamine Receptor to Regulate Cell Surface Expression and Desensitization, Journal of Neuroscience, 2002, vol. 22, pp. 5920-5930. Full Text/Abstract

2001

Schetz, J.A. and Sibley, D.R.
The Binding Site Crevice of the D4 receptor is Coupled to Three Unique Sites of Allosteric Regulation, Journal of Pharmacology and Experimental Therapeutics, 2001, vol. 296, pp. 359-363. Full Text/Abstract

Gardner, B. Liu, Z.F., Jiang, D., and Sibley, D.R.
The Role of Phosphorylation/Dephosphorylation in Agonist-Induced Desensitization of D1 Receptor Function: Evidence for a Novel Pathway for Receptor Dephosphorylation, Molecular Pharmacology, 2001, vol. 59, pp. 310-321. Full Text/Abstract

Holmes, A., Hollon, T.R., Gleason, T.C., Liu, Z., Dreiling, J., Sibley, D.R., and Crawley, J.N.,
Dopamine D5 Receptor Null Mutant Mice Show Attenuated Behavioral Responses to a Dopamine Agonist, Behavioral Neuroscience, 2001, vol. 115, pp. 1129-1144.

Hunyady, B., Toth, Z., Palkovits, M., Mossik, G., Molnar, J., Feher, K., Zolyomi, A., Sibley, D.R. and Mezey, E.
Susceptibility of Dopamine D5 Receptor Targeted Mice to Cysteamine, Journal of Physiology (Paris), 2001, vol. 95(1-6), pp. 147-151. Full Text/Abstract

2000

Ventura, A.L.M and Sibley, D.R.
Altered Regulation of the D1 Dopamine Receptor in Mutant Chinese Hamster Ovary Cells Deficient in Cyclic AMP-dependent Protein Kinase Activity, Journal of Pharmacology and Experimental Therapeutics, 2000, vol. 293, pp. 426-434. Full Text/Abstract

Schetz, J.A. and Sibley, D.R.
Tandem Sulfer-Containing Amino Acids are Epicritical Determinants of D2 Dopamine Receptor Pharmacology, European Journal of Pharmacology, 2000, vol. 388, pp. R5-R7. Full Text/Abstract

Schetz, J.A., Benjamin, P.S., and Sibley, D.R.
Non-Conserved Residues in the Second Transmembrane-Spanning Domain of the D4 Dopamine Receptor are Molecular Determinants of D4-Selective Pharmacology, Molecular Pharmacology, 2000, vol. 57, pp. 144-152. Full Text/Abstract

1999

Schetz, J.A., Chu, A., and Sibley, D.R.
Zinc Modulates Antagonist Interactions with D2-like Dopamine Receptors Through Distinct Molecular Mechanisms, Journal of Pharmacology and Experimental Therapeutics, 1999, vol. 289, pp. 956-964. Full Text/Abstract

Sibley, D.R.
New Insights Into Dopaminergic Receptor Function Using Antisense and Genetically Altered Animals, Annual Review of Pharmacology and Toxicology, 1999, vol. 39, pp. 313-341. Full Text/Abstract

Jiang, D. and Sibley, D.R.
Agonist-induced Desensitization of D1 Dopamine Receptors with Mutations of Cyclic AMP-dependent Protein Kinase Phosphorylation Sites: Attenuation of the Rate of Agonist-induced Desensitization, Molecular Pharmacology, 1999, vol. 56, pp. 675-683. Full Text/Abstract

El-Ghundi, M., Fletcher, P.J., Drago, J., Sibley, D.R., O'Dowd, B.F., and George, S.R.
Spatial Learning Deficit in Dopamine D1 Receptor Knockout Mice, , European Journal of Pharmacology, 1999, vol. 383, pp. 95-106. Full Text/Abstract

Clifford, J.J., Tighe, O., Croke, D.T., Kinsella, A., Sibley, D.R., Drago, J. and Waddington, J.L.
Conservation of Behavioral Topography to Dopamine D1-like Receptor Agonists in Mutant Mice Lacking the D1A Receptor Implicates a D1-like Receptor not Coupled to Adenylyl Cyclase, Neuroscience, 1999, vol. 93, pp. 1483-1489. Full Text/Abstract

Cepeda, C., Li, Z., Cromwell, H.C., Altemus, K.L., Crawford, C.A., Nansen, E.A., Ariano, M.A., Sibley, D.R., Peacock, W.J., Mathern, G.G., and Levine, M.S.
Electrophysiological and Morphological Analyses of Cortical Neurons Obtained from Childen with Catastrophic Epilepsy: Dopamine Receptor Modulation of Glutaminergic Responses, Developmental Neuroscience, 1999, vol. 21, pp. 223-235. Full Text/Abstract

Schetz, J.A. and Sibley, D.R.
Metal Cations as Atomic Scale Probes of G-Protein Coupled Receptor Structure and Function, Receptor Biochemistry and Methodology, 1999, vol. 3, pp. 121-140.

Lawler, C.P., Prioleau, C., Lewis, M.M., Mak, C., Jiang, D., Schetz, J.A., Gonzalez, A.M., Sibley, D.R. and Mailman, R.B.
The Molecular Pharmacology of the Novel Antipsychotic Aripiprazole (OPC-14597), Neuropsychopharmacology, 1999, vol. 20, pp. 612-627. Full Text/Abstract

Cravchik, A., Sibley, D.R., and Gejman, P.V.
Differences in Neuroleptic Activity at the Human D2 Dopamine Receptor Missense Variants, Pharmacogenetics, 1999, vol. 9, pp. 17-23. Full Text/Abstract

Clifford, J.J., Tighe, O., Croke, D.T., Sibley, D.R., Drago, J., and Waddington, J.L.
Ethologically-based Topographical Evaluation of the Phenotype of Spontaneous Behaviour in Mice with Targeted Deletion of the D1A Dopamine Receptor: Paradoxical Elevation of Grooming Syntax, Neuroharmacology, 1999, vol. 37, pp. 1595-1602. Full Text/Abstract

Liu, L.-X., Burgess, L.H., Gonzalez, A.M., Sibley, D.R. and Chiodo, L.A.
D2S, D2L, D3 and D4 Dopamine Receptors Couple to a Voltage-Dependent Potassium Current in N18TG2 X Mesencephalon Hybrid Cells (MES-23.5) via Distinct G Proteins, Synapse, 1999, vol. 31, pp. 108-118. Full Text/Abstract

201

Rankin, M.L., and Sibley, D.R.
Consitutive phosphorylation by protein kinase C regulates D1 dopamine receptor signaling, Journal of Neurochemistry, 201, vol. 115, pp. 1655-1667. Full Text/Abstract

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