Axon Guidance and Neural Connectivity Unit - Division of Intramural Research

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Le Gall, M. and Giniger, E.
Identification of two binding regions for the Suppressor of Hairless protein within the intracellular domain of Drosophila Notch - J. Biol. Chem   279 29418-29426 2004

Horiuchi, T. Giniger, E. and Aigaki, T.
Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola - Genes Dev   17 2496-2501 2003

Goeke, S., Greene, E.A., Gates, M.A., Grant, P.K., Crowner, D., Aigaki, T. and Giniger, E.
Alternative splicing of lola generates 19 transcription factors controlling axon guidance in Drosophila - Nature Neuroscience   6 917-924 2003

Crowner, D., Le Gall, M., Gates, M.A., and Giniger, E.
Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway - Curr Biol   13 967-972 2003

Crowner, D., Madden, K., Goeke, S. and Giniger, E.
Lola regulates midline crossing of CNS axons in Drosophila - Development  129 1317-1325 2002

Giniger, E.
How do Rho family GTPases direct axon growth and guidance? A proposal relating signaling pathways to growth cone mechanics - Differentiation   70 385-396 2002

Hiramoto, M., Hiromi, Y., Giniger, E. and Hotta, Y.
A Drosophila Netrin receptor, Frazzled, guides axons by controlling the distribution of Netrin - Nature   406 886-889 2000

Bothwell, M. and Giniger, E.
Alzheimer's Disease: Neurodevelopment Converges with Neurodegeneration - Cell   102 271-273 2000

Connell-Crowley, L., Le Gall, M., Vo, D. and Giniger, E.
Cdk5 controls multiple aspects of axon patterning in vivo. - Curr Biol   10 599-602 2000

Madden, K., Crowner, D. and Giniger, E.
lola has the properties of a master regulator of axon-target interactions for SNb motor axons of Drosophila - Dev. Biol  301-313 213 1999

Ostrander, E. A. and Giniger, E.
Let sleeping dogs lie? - Nature Genetics   23 3-4 1999

Fuerstenberg, S. M. and Giniger, E.
Multiple roles for Notch in Drosophila myogenesis - Dev. Biol  201 66-77 1998

Ostrander, E. A. and Giniger, E.
What man's best friend can teach us about human biology and disease - Am. J. Hum. Genet  61 475-80 1997

Larkin, M. K., Holder, K., Yost, C., Giniger, E. and Ruohola-Baker, H.
Expression of constitutively active Notch arrests follicle cells at a precursor stage during Drosophila oogenesis and disrupts the anterior-posterior axis of the oocyte - Development   3639-3650 122 1996

Giniger, E., Tietje, K., Jan, L. Y. and Jan, Y. N.
lola encodes a putative transcription factor required for axon growth and guidance in Drosophila - Development   120 1385-98 1994

Clark, I., Giniger, E., Ruohola-Baker, H., Jan, L. Y. and Jan, Y. N.
Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte - Curr. Biol  4 289-300 1994

Giniger, E., Jan, L. Y. and Jan, Y. N.
Specifying the path of the intersegmental nerve of the Drosophila embryo: a role for Delta and Notch - Development   117 431-440 1993

Giniger, E., Wells, W., Jan, L. Y. and Jan, Y. N.
Tracing neurons with a kinesin-ƒÒ-galactosidase fusion protein. - Roux's Arch Dev Biol   202 112-122 1993

Giniger, E.
A role for abl in Notch signaling - Neuron   20 667-681 1988

Giniger, E. and Ptashne, M.
Cooperative binding of the yeast transcriptional activator, GAL4 - Proc Natl Acad Sci, USA   85 382-386 1988

Fischer, J. A., Giniger, E., Maniatis, T. and Ptashne, M.
GAL4 activates transcription in Drosophila. - Nature   332 853-856 1988

Giniger, E. and Ptashne, M.
Transcription in yeast activated by a putative amphipathic ƒÑ-helix linked to a DNA-binding unit - Nature   330 670-672 1987

Giniger, E., Varnum, S. M. and Ptashne, M.
Specific DNA binding of GAL4, a positive regulatory protein of yeast. - Cell   40 767-774 1985

Wagner, P. D. and Giniger, E.
Calcium-sensitive binding of heavy meromyosin to regulated actin in the presence of ATP - J Biol Chem   256 12647-12650 1981

Wagner, P. D. and Giniger, E.
Hydrolysis of ATP and reversible binding to F-actin by myosin heavy chains free of all light chains - Nature   292 560-562 1981

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