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Axon Guidance and Neural Connectivity Unit - Division of Intramural Research



2011

Kuzina, I., Song, J.K. and Giniger, E.
How Notch establishes longitudinal axon connections between successive segments of the Drosophila CNS, Development, 2011, vol. 138, pp. 1839-49.

Trunova, S., Baek, B. and Giniger, E.
Cdk5 regulates the size of an AIS-like compartment in mushroom body neurons of the Drosophila central brain, J. Neurosci, 2011, vol. 31, pp. 10451-62.

2010

Song, J.K., Kannan, R., Merdes, G., Singh, J., Mlodzik, M. and Giniger, E.
Disabled is a bona fide component of the Abl signaling network, Development, 2010, vol. 137, pp. 3719-3727.

2008

Le Gall, M., DeMattei, C. and Giniger, E.
Molecular separation of two signaling pathways for the receptor, Notch, Dev. Biol, 2008, vol. 313, pp. 556-567.

2007

Connell-Crowley, L., Vo, D., Luke, L. and Giniger, E.
Drosophila lacking the Cdk5 activator, p35, display defective axon guidance, age-dependent behavioral deficits and reduced lifespan, Mech of Dev, 2007, vol. 124, pp. 341-9.

2004

Le Gall, M. and Giniger, E.
Identification of two binding regions for the Suppressor of Hairless protein within the intracellular domain of Drosophila Notch, J. Biol. Chem, 2004, vol. 279, pp. 29418-29426.

2003

Horiuchi, T. Giniger, E. and Aigaki, T.
Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola, Genes Dev, 2003, vol. 17, pp. 2496-2501.

Goeke, S., Greene, E.A., Gates, M.A., Grant, P.K., Crowner, D., Aigaki, T. and Giniger, E.
Alternative splicing of lola generates 19 transcription factors controlling axon guidance in Drosophila, Nature Neuroscience, 2003, vol. 6, pp. 917-924.

Crowner, D., Le Gall, M., Gates, M.A., and Giniger, E.
Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway, Curr Biol, 2003, vol. 13, pp. 967-972.

2002

Crowner, D., Madden, K., Goeke, S. and Giniger, E.
Lola regulates midline crossing of CNS axons in Drosophila, Development, 2002, vol. 129, pp. 1317-1325.

Giniger, E.
How do Rho family GTPases direct axon growth and guidance? A proposal relating signaling pathways to growth cone mechanics, Differentiation, 2002, vol. 70, pp. 385-396.

2000

Hiramoto, M., Hiromi, Y., Giniger, E. and Hotta, Y.
A Drosophila Netrin receptor, Frazzled, guides axons by controlling the distribution of Netrin, Nature, 2000, vol. 406, pp. 886-889.

Bothwell, M. and Giniger, E.
Alzheimer's Disease: Neurodevelopment Converges with Neurodegeneration, Cell, 2000, vol. 102, pp. 271-273.

Connell-Crowley, L., Le Gall, M., Vo, D. and Giniger, E.
Cdk5 controls multiple aspects of axon patterning in vivo., Curr Biol, 2000, vol. 10, pp. 599-602.

1999

Madden, K., Crowner, D. and Giniger, E.
lola has the properties of a master regulator of axon-target interactions for SNb motor axons of Drosophila, Dev. Biol, 1999, vol. 301-313, pp. 213.

Ostrander, E. A. and Giniger, E.
Let sleeping dogs lie?, Nature Genetics, 1999, vol. 23, pp. 3-4.

1998

Fuerstenberg, S. M. and Giniger, E.
Multiple roles for Notch in Drosophila myogenesis, Dev. Biol, 1998, vol. 201, pp. 66-77.

1997

Ostrander, E. A. and Giniger, E.
What man's best friend can teach us about human biology and disease, Am. J. Hum. Genet, 1997, vol. 61, pp. 475-80.

1996

Larkin, M. K., Holder, K., Yost, C., Giniger, E. and Ruohola-Baker, H.
Expression of constitutively active Notch arrests follicle cells at a precursor stage during Drosophila oogenesis and disrupts the anterior-posterior axis of the oocyte, Development, 1996, vol. 3639-3650, pp. 122.

1994

Giniger, E., Tietje, K., Jan, L. Y. and Jan, Y. N.
lola encodes a putative transcription factor required for axon growth and guidance in Drosophila, Development, 1994, vol. 120, pp. 1385-98.

Clark, I., Giniger, E., Ruohola-Baker, H., Jan, L. Y. and Jan, Y. N.
Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte, Curr. Biol, 1994, vol. 4, pp. 289-300.

1993

Giniger, E., Jan, L. Y. and Jan, Y. N.
Specifying the path of the intersegmental nerve of the Drosophila embryo: a role for Delta and Notch, Development, 1993, vol. 117, pp. 431-440.

Giniger, E., Wells, W., Jan, L. Y. and Jan, Y. N.
Tracing neurons with a kinesin-ƒÒ-galactosidase fusion protein., Roux's Arch Dev Biol, 1993, vol. 202, pp. 112-122.

1988

Giniger, E.
A role for abl in Notch signaling, Neuron, 1988, vol. 20, pp. 667-681.

Giniger, E. and Ptashne, M.
Cooperative binding of the yeast transcriptional activator, GAL4, Proc Natl Acad Sci, USA, 1988, vol. 85, pp. 382-386.

Fischer, J. A., Giniger, E., Maniatis, T. and Ptashne, M.
GAL4 activates transcription in Drosophila., Nature, 1988, vol. 332, pp. 853-856.

1987

Giniger, E. and Ptashne, M.
Transcription in yeast activated by a putative amphipathic Ą-helix linked to a DNA-binding unit, Nature, 1987, vol. 330, pp. 670-672.

1985

Giniger, E., Varnum, S. M. and Ptashne, M.
Specific DNA binding of GAL4, a positive regulatory protein of yeast., Cell, 1985, vol. 40, pp. 767-774.

1981

Wagner, P. D. and Giniger, E.
Calcium-sensitive binding of heavy meromyosin to regulated actin in the presence of ATP, J Biol Chem, 1981, vol. 256, pp. 12647-12650.

Wagner, P. D. and Giniger, E.
Hydrolysis of ATP and reversible binding to F-actin by myosin heavy chains free of all light chains, Nature, 1981, vol. 292, pp. 560-562.

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