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Membrane Transport Biophysics Section - Division of Intramural Research


Compton ELR, Taylor EM, Mindell JA
The 3-4 loop of an archael glutamate transporter homolog experiences ligand-induced structural changes and is essential for transport, PNAS, 2010, vol. doi/10.1073/pnas.1003046107


Ryan RM, Compton, ELR, Mindell JA
Functional characterization of a Na+-dependent aspartate transporter from Pyrococcus horikoshii., Journal of Biological Chemistry, 2009, vol. 284, pp. 17540-8.


Graves AR. Curran PK, Smith CL, Mindell JA
The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes, Nature, 2008, vol. doi:10.1038/nature06907 Full Text/Abstract

Osteen J and Mindell JA
Insights into the ClC-4 transport mechanism from studies of Zn2+ inhibition., Biophysical Journal, 2008, vol. 95, pp. 4668-75.


Ryan RM and Mindell JA
The uncoupled chloride conductance of a bacterial glutamate, Nature Structural and Molecular Biology, 2007, vol. 14, pp. 365-71. Full Text/Abstract


Bell SP, Curran PK, Choi S, and JA Mindell
Site-directed fluorescence studies of a prokaryotic ClC transporter, Biochemistry, 2006, vol. 45, pp. 6773.


Phillips LR, Milescu M, Li-Smerin Y, Mindell JA, Kim JI, Swartz KJ
Voltage-sensor activation with a tarantula toxin as cargo, Nature, 2005, vol. 436, pp. 857-60.


Maduke M and Mindell JA
The poststructural festivities begin, Neuron, 2003, vol. 38, pp. 1-3.

Mindell JA and Grigorieff N
Accurate determination of local defocus and specimen tilt in electron microscopy, J Struct Biol, 2003, vol. 142, pp. 334-7.


Mindell JA, Maduke M
ClC Chloride Channels, Genome Biology, 2001, vol. 2, pp. 3003.

Mindell JA, Maduke M, Miller C, Grigorieff N
Projection structure of a ClC-type Cl- channel at 6.5 angstrom resolution, Nature, 2001, vol. 409, pp. 219. Full Text/Abstract


Maduke M, Miller C, Mindell JA
A Decade of ClC chloride channels: structure, mechanism, and many unsettled questions, Ann Rev Biophys and Biomol Structure, 2000, vol. 29, pp. 411. Full Text/Abstract


Mindell JA
Commentary: Swimming through the hydrophobic sea: New insights in protein translocation, Proc Natl Acad Sci U S A, 1998, vol. 95, pp. 4081. Full Text/Abstract


Mindell JA, Zhan H, Huynh PD, Collier RJ and Finkelstein A
Reaction of diphtheria toxin channels with sulfhydryl-specific reagents: observation of chemical reactions at the single molecule level, Proc Natl Acad Sci U S A, 1994, vol. 91, pp. 5272. Full Text/Abstract

Silverman JA, Mindell JA, Finkelstein A, Shen WH, Collier RJ
Mutational analysis of the helical hairpin region of diphtheria toxin transmembrane domain, J Biol Chem, 1994, vol. 269, pp. 22524. Full Text/Abstract

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