Molecular Neurophysiology Section - Division of Intramural Research

Gadsby, D.C., Bezanilla, F., Rakowski, R.F., De Weer, P. and Holmgren
The dynamic relationships between the three events that release individual Na+ ions from the Na+/K+-ATPase - Nature Communications  3 669 doi:1038/ncomms1673 2012

Sandtner, W., Egwolf, B., Khalili-Araghi, F., Sanchez-Rodriguez, J.E., Roux, B., Bezanilla, F. and Holmgren, M.
Ouabain binding site in a functioning Na+/K+-ATPase.  - J. Biol. Chem.   286 38177-38183. 2011

Castillo J.P., De Giorgis D., Basilio, D., Gadsby, D.C., Rosenthal, J.J., Latorre, R., Holmgren, M., Bezanilla,
Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the axon of the Humboldt squid.  - Proc. Nat. Acad. Sci. USA   108 20556-20561 2011

Gonzalez, C., Lopez-Rodriguez, A., Srikumar, D., Rosenthal, J.J.C. and Holmgren, M.
Editing of human KV1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity. - Nat. Commun.   2 436 doi: 10.1038/ncomms1446 2011

Galarza, G. Soto, S.I., Holmgren M. and Rosenthal, J.J.C
Physiological Adaptation of an Antarctic Na+/K+-ATPase to the cold. - J. Exp. Biol.  214 2164-2174 2011

Colina, C., Palavicini, J.P., Srikumar, D., Holmgren, M. and Rosenthal, J.J.C
Regulation of Na+/K+ ATPase transport velocity by RNA editing. - PLoS Biol.   8 e1000540 2010

Contreras, J.E., Chen, J., Lau, A.Y., Jogini, V., Roux, B. and Holmgren, M
Voltage profile along the permeation pathway of an open channel. - Biophys. J.  99 2863-2869 2010

Contreras, J.E. Srikumar, D. and Holmgren, M.
Gating at the selectivity filter in cyclic nucleotide-gated channels - PNAS  105 3310-3314 2008

Colina, C., J.J.C. Rosenthal, J.A. DeGiorgis, D. Srikumar, N. Iruku& M. Holmgren
Structural basis of Na+/K+-ATPase adaptation to marine environments - Nature Structural Molecular Biology  14 427-431 2007

Holmgren, M. and Rakowski, RF.
Charge Translocation by the Na+/K+ Pump under Na+/Na+ Exchange Conditions: Intracellular Na+ Dependence - Biophys. J.  90 1607-16 2006

Contreras, JE and Holmgren, M.
Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate. - J. Gen. Physiol.  127 481-94 2006

Bhalla, T., Rosenthal, JJC, Holmgren, M., and Reenan, R.
Control of Human Potassium Channel Inactivation by Editing of a Small mRNA Hairpin - Nature Structural & Molecular Biology  11 950-956 2004

Holmgren, Miguel
Influence of Permeant Ions on Gating in Cyclic Nucleotide-gated Channels - J. Gen Physiol  121 61-72 2003

Soler-Llavina GJ, Holmgren M, and Swartz KJ
Defining the Conductance of the Closed State in a Voltage-Gated K+ Channel - Neuron  38 61-67 2003

Holmgren M, Wagg J, Bezanilla F, Rakowski RF, De Weer P and Gadsby DC
Three distinct and sequential steps in the release of sodium ions by the Na+/K+-ATPase - Nature  403(6772) 898-901 2000

del Camino D, Holmgren M, Liu Y, Yellen G.
Blocker protection in the pore of a voltage-gated K+ channel and its structural implications - Nature  403(6767) 321-5 2000

Holmgren M, Shin KS, Yellen G
The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge - Neuron  21(3) 617-21 1998

Liu Y, Holmgren M, Jurman ME, Yellen G.
Gated access to the pore of a voltage-dependent K+ channel - Neuron  19(1) 175-84 1997

Holmgren M, Rakowski RF.
Pre-steady-state transient currents mediated by the Na/K pump in internally perfused Xenopus oocytes - Biophys J  66(3 Pt 1) 912-22 1994

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