Developmental Neurobiology Section - Division of Intramural Research

2013

Thirumalai V, Behrend RM, Birineni S, Liu W, Blivis D, O'Donovan MJ
2. Preservation of VGLUT1 synapses on ventral calbindin-immunoreactive interneurons and normal locomotor function in a mouse model of spinal muscular atrophy, J Neurophysiol, 2013, vol. 109, pp. 702-10. Full Text/Abstract

Etlin A, Finkel E, Mor Y, O'Donovan MJ, Anglister L, Lev-Tov A
Characterization of sacral interneurons that mediate activation of locomotor pattern generators by sacrocaudal afferent input, J Neurosci, 2013, vol. 33, pp. 734-47. Full Text/Abstract

2012

Haspel G, O'Donovan MJ
A connectivity model for the locomotor network of Caenorhabditis elegans, Worm, 2012, vol. 1, pp. 125-128. Full Text/Abstract

Blivis D, O'Donovan MJ
Retrograde loading of nerves, tracts, and spinal roots with fluorescent dyes, J Vis Exp, 2012, vol. 62, pp. e4008. Full Text/Abstract

2011

Mentis GZ, Blivis D, Liu W, Drobac E, Crowder ME, Kong L, Alvarez FJ, Sumner CJ, O'Donovan MJ
Early functional impairment of sensory-motor connectivity in a mouse model of spinal muscular atrophy, Neuron, 2011, vol. 69, pp. 453-67. Full Text/Abstract

Haspel G, O'Donovan MJ
A perimotor framework reveals functional segmentation in the motoneuronal network controlling locomotion in Caenorhabditis elegans, J Neurosci, 2011, vol. 31, pp. 14611-23. Full Text/Abstract

2010

Haspel G, O'Donovan MJ, Hart AC.
Motoneurons dedicated to either forward or backward locomotion in the nematode Caenorhabditis elegans., J Neurosci., 2010, vol. 33, pp. 11151-6.. Full Text/Abstract

Mentis GZ, Alvarez FJ, Shneider NA, Siembab VC, O'Donovan MJ.
Mechanisms regulating the specificity and strength of muscle afferent inputs in the spinal cord., Ann N Y Acad Sci., 2010, vol. 1198, pp. 220-30.. Full Text/Abstract

O'Donovan MJ, Bonnot A, Mentis GZ, Chub N, Pujala A, Alvarez FJ.
Mechanisms of excitation of spinal networks by stimulation of the ventral roots., Ann N Y Acad Sci., 2010, vol. 1198, pp. 63-71.. Full Text/Abstract

Jovanovic K, Pastor AM, O'Donovan MJ.
The use of PRV-Bartha to define premotor inputs to lumbar motoneurons in the neonatal spinal cord of the mouse., PLoS One, 2010, vol. 5(7), pp. e11743.. Full Text/Abstract

2009

Bonnot A, Chub NL, Pujala A, O'Donovan MJ.
Excitatory actions of ventral root stimulation during network activity generated by the disinhibited neonatal mouse spinal cord., J Neurophysiol., 2009, vol. Epub, Mar.25 Full Text/Abstract

Fields DR, Shneider N, Mentis GZ, O'Donovan MJ.
Imaging nervous system activity., Curr Protoc Neurosci., 2009, vol. Chapter 2:, pp. Unit 2.3. Full Text/Abstract

Shneider NA, Mentis GZ, Schustak J, O'Donovan MJ.
Functionally reduced sensorimotor connections form with normal specificity despite abnormal muscle spindle development: the role of spindle-derived neurotrophin 3., J Neurosci., 2009, vol. 29, pp. 4719-35.. Full Text/Abstract

2008

Vladimirski BB, Tabak J, O'Donovan MJ, Rinzel J.
Episodic activity in a heterogeneous excitatory network, from spiking neurons to mean field., J Comput Neurosci., 2008, vol. 25, pp. 39-63. Full Text/Abstract

O'Donovan MJ, Bonnot A, Mentis GZ, Arai Y, Chub N, Shneider NA, Wenner P.
Imaging the spatiotemporal organization of neural activity in the developing spinal cord., Dev Neurobiol., 2008, vol. 68, pp. 788-803. Full Text/Abstract

2007

Jean-Xavier C, Mentis GZ, O'Donovan MJ, Cattaert D, and Vinay L
Dual personality of GABA/glycine-mediated depolarizations in immature spinal cord, PNAS, 2007, vol. 104, pp. 11477-11482. Full Text/Abstract

Arai Y, Mentis GZ, Wu J and O'Donovan MJ
Ventrolateral origin of activity during each cycle of spontaneous activity generated by the spinal cord of the chick embryo, PLoS ONE, 2007, vol. 2(5), pp. e317. Full Text/Abstract

Personius KE, Chang Q, Mentis GZ, O'Donovan MJ, Balice-Gordon RJ.
Reduced gap junctional coupling leads to uncorrelated motor neuron firing and precocious neuromuscular synapse elimination., PNAS, 2007, vol. 104, pp. 11808-13. Full Text/Abstract

Oz M, Yang KH, Shippenberg TS, Renaud LP, O'Donovan MJ
Cholecystokinin B type receptors mediate a G protein-dependent depolarizing action of cholecystokinin (CCK-8s) on rodent neonatal spinal ventral horn neurons., J.Neurophysiol., 2007, vol. 98, pp. 1108-14. Full Text/Abstract

Blivis D, Mentis GZ , O'Donovan MJ and Lev-Tov A
Interaction between afferent pathways and central pattern generators in the neonatal rat spinal cord, J. Neurophysiol., 2007, vol. 97, pp. 2875-2886. Full Text/Abstract

2006

Tabak J, O'Donovan MJ and Rinzel J
Differential control of active and silent phases in relaxation models of neuronal rhythms, J. Comp. Neurosci., 2006, vol. 21, pp. 307-328. Full Text/Abstract

Mentis GZ, Gravell M, Hamilton R, Shneider NA, O'Donovan MJ and Schubert M
Transduction of Motor Neurons and Muscle Fibers by Intramuscular Injection of HIV-1-based Vectors Pseudotyped with Select Rabies Virus Glycoproteins, J.Neurosci.Meth., 2006, vol. 157, pp. 208-217. Full Text/Abstract

Chub N, Mentis GZ and O'Donovan MJ
Chloride-Sensitive MEQ Fluorescence in Chick Embryo Motoneurons Following Manipulations of Chloride and During Spontaneous Network Activity, J.Neurophysiol, 2006, vol. 95, pp. 323-330. Full Text/Abstract

Mentis GZ, Siembab VC, Zerda R, O'Donovan MJ and Alvarez FJ
Primary afferent synapses on developing Renshaw cells, J. Neurosci., 2006, vol. 26, pp. 13297-13310. Full Text/Abstract

2005

Mentis GZ, Alvarez FJ, Bonnot A, Richards DS, Gonzalez-Forero D, Zerda R and O'Donovan MJ
Non-cholinergic excitatory actions of motoneurons in the neonatal mammalian spinal cord., PNAS, 2005, vol. 102, pp. 7344-7349. Full Text/Abstract

Marchetti C, Tabak J, Chub N, O'Donovan MJ and Rinzel J
Model of spontaneous activity in the developing spinal cord using activity-dependent variations of intracellular chloride, J. Neurosci, 2005, vol. 25, pp. 3601-3612. Full Text/Abstract

Bonnot A, Mentis GZ, Skoch J and O'Donovan MJ
Electroporation Loading of Calcium Sensitive Dyes into the Central Nervous System, J. Neurophysiol, 2005, vol. 93, pp. 1793-1808. Full Text/Abstract

O'Donovan MJ, Bonnot A, Wenner P, Mentis GZ
Calcium imaging of network function in the developing spinal cord., Cell Calcium, 2005, vol. 37, pp. 443-450. Full Text/Abstract

Oz M, Yang SK, O'Donovan MJ and Renaud LP
Presynaptic Angiotensin II AT1 Receptors Enhance Inhibitory and Excitatory Synaptic Neurotransmission to Motoneurons and other Ventral Horn Neurons in Neonatal Rat Spinal Cord, J.Neurophysiol, 2005, vol. 94, pp. 1405-1412. Full Text/Abstract

2002

Bonnot A, Whelan P, Mentis GZ and O'Donovan MJ
Spatiotemporal pattern of motoneuron activation in the rostral lumbar and sacral segments during locomotor-like activity in the neonatal mouse spinal cord, J. Neurosci., 2002, vol. 22, pp. RC203. Full Text/Abstract

2001

Tabak J, Rinzel J and O'Donovan, MJ
The role of activity-dependent network depression in the expression and self-regulation of spontaneous activity in the developing spinal cord of the chick embryo, J. Neurosci., 2001, vol. 21, pp. 8966-8978. Full Text/Abstract

Chub N and O'Donovan MJ
Post-Episode Depression of GABAergic transmission in spinal neurons of the chick embryo, J. Neurophysiol, 2001, vol. 85, pp. 2166-2176. Full Text/Abstract

Wenner P and O'Donovan MJ
Mechanisms that initiate spontaneous network activity in the developing chick spinal cord, J. Neurophysiol., 2001, vol. 86, pp. 1481-1498. Full Text/Abstract

2000

Tabak J, Senn W, O'Donovan MJ, and Rinzel J
Modeling of spontaneous activity in developing spinal cord using activity-dependent network depression in an excitatory network., J. Neurosci., 2000, vol. 20, pp. 3041-3056. Full Text/Abstract

Wenner P, O'Donovan MJ and Matise MP
Topographical and physiological characterization of interneurons that express the Engrailed-1 homeodomain transcription factor in the embryonic chick spinal cord., J. Neurophysiol., 2000, vol. 84, pp. 2651-2658. Full Text/Abstract

Whelan P, Bonnot A and O'Donovan MJ
Properties of rhythmic activity generated by the isolated spinal cord of the neonatal mouse, J. Neurophysiol., 2000, vol. 84, pp. 2821-2833. Full Text/Abstract

Sernagor E, Eglen SJ, O'Donovan MJ
Differential effects of acetylcholine and glutamate blockade on the spatiotemporal dynamics of retinal waves, J.Neurosci., 2000, vol. 20, pp. RC56:1-6. Full Text/Abstract

1999

O'Donovan MJ
The origin of spontaneous activity in developing networks of the vertebrate nervous system, Curr. Opin. Neurobiol., 1999, vol. 9, pp. 94-104. Full Text/Abstract

Moore LE, ChubN, Tabak J, O'Donovan M
Comparison of NMDA-induced membrane potential oscillations and spontaneous rhythmic activity in the chick spinal cord, J. Neurosci., 1999, vol. 19, pp. 8271-8280. Full Text/Abstract

Fedirchuk B, Wenner P, Whelan PJ, Ho S, Tabak J, O'Donovan MJ
Spontaneous network activity transiently depresses synaptic transmission in the embryonic chick spinal cord, J. Neurosci., 1999, vol. 19, pp. 2102-2112. Full Text/Abstract

Wenner P, O'Donovan MJ
Identification of an interneuronal population that mediates recurrent inhibition of motoneurons in the developing chick spinal cord, J. Neurosci., 1999, vol. 19, pp. 7557-7567. Full Text/Abstract

Ritter A, Wenner P, HoS, Whelan PJ, O'Donovan MJ
Activity patterns and synaptic organization of ventrally located interneurons in the embryonic chick spinal cord, J.Neurosci., 1999, vol. 19, pp. 3457-3471. Full Text/Abstract

1998

Chub N and O'Donovan MJ
Blockade and recovery of spontaneous rhythmic activity following application of neurotransmitter antagonists to spinal networks of the chick embryo., J. Neurosci., 1998, vol. 18, pp. 294-306. Full Text/Abstract

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