Mammalian Development Section - Division of Intramural Research

Bauer, GL, Christian, P, Bergsteinsdottir, K, et al.
The role of MITF phosphorylation sites during coat color and eye development in mice analyzed by BAC transgene rescue - Genetics    2009

Skuntz, S, Mankoo, B, Nguyen, MTT, Hustert, E, Nakayama, A, Tournier-Lasserve, E, Wright, CVE, Pachnis, V, Bharti, K, Arnheiter, H.
Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton - Developmental Biology  332 383-395 2009

Heinz Arnheiter and Kapil Bharti
Ribosomes and p53 - a new KIT for skin darkening - Pigment Cell and Melanoma Research    2008

Bharti, K, Liu, W, Csermely, T, Bertuzzi, S, Arnheiter, H.
Alternative promoter use in eye development: the complex role and regulation of the transcription factor MITF - Development  135 1169-1178 2008

Bismuth, K., Skuntz, S., Hallsson, J.H., Pak, P., Dutra, A.B., Steingrimsson, E., Arnheiter, H.
An unstable targeted allele of the mouse Mitf gene with a high somatic and germ line reversion rate - Genetics  178 259-272 2008

Arnheiter, H.
Mammalian paramutation: a tail's tale? - Pig Cell Res  20 36-40 2007

Hallsson, JH, Haflidadottir, BS, Schepsky, A, Arnheiter, H, Steingrimsson, E
Evolutionary sequence comparison of the Mitf gene reveals novel conserved domains - Pigment Cell Research  20 185-200 2007

Bharti, K., Nguyen, M.-T. T., Skuntz, S., Nakayama, A., Bertuzzi, S., and Arnheiter, H.
The other pigment cell: Specification and development of the pigmented epithelium of the vertebrate eye - Pigment Cell Research  19 380-394 2006

Hou, L., Arnheiter, H. and Pavan, W.J.
Interspecies difference in the regulation of melanocyte development by SOX10 and MITF - Proc. Natl. Acad. Sci. (USA)  103 9081-9085 2006

Horsford, D.J., Nguyen, M.T.T., Sellar, G., De Repentigny, Y., Kothary, R., Arnheiter, H., and McInnes, R.R.
Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity - Development  132 177-187 2005

Potterf SB, Furumura M, Dunn KJ, Arnheiter H, Pavan WJ
Transcription factor hierarchy in Waardenburg syndrome: Regulation of MITF expression by SOX10 and PAX3 - Human Genet    2000

Nguyen M-T T and Arnheiter H
Signaling and transcriptional regulation in early mammalian eye development: A link between FGF and MITF  - Development  127 3581-3591 2000

Hou L., Panthier J.-J., Arnheiter, H.
Signaling and transcription regulation in the neural crest-derived melanocyte lineage: Interactions between KIT and MITF - Development  127 5379-5389 2000

Arnheiter H.
Evolutionary biology. Eyes viewed from the skin - Nature  391 632-633 1998

Opdecamp K, Vanvooren P, Riviere M, Arnheiter H, Motta R, Szpirer J, Szpirer C.
The rat microphthalmia-associated transcription factor gene (Mitf) maps at 4q34-q41 and is mutated in the mib rats - Mamm Genome  9 617-621 1998

Hampton LL, Ladenheim EE, Akeson M, Way JM, Weber HC, Sutliff VE, Jensen RT, Wine LJ, Arnheiter H, Battey JF.
Loss of bombesin-induced feeding suppression in gastrin-releasing peptide receptor-deficient mice. - Proc Natl Acad Sci USA  95 3188-3192 1998

Opdecamp K, Kos L, Arnheiter H, Pavan WJ.
Endothelin signalling in the development of neural crest-derived melanocytes - Biochem Cell Biol.   76 1093-1099 1998

Hodgkinson CA, Nakayama A, Li H, Swenson LB, Opdecamp K, Asher JH Jr, Arnheiter H, Glaser T.
Mutation at the anophthalmic white locus in Syrian hamsters: haploinsufficiency in the Mitf gene mimics - Hum Mol Genet  7 703-708 1998

Nakayama A et al.
Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently - Mech Dev  70 155-166 1998

Krylov D, Kasai K, Echlin DR, Taparowsky EJ, Arnheiter H, Vinson C.
A general method to design dominant negatives to B-HLHZip proteins that abolish DNA binding. - Proc Natl Acad Sci USA  94 12274-9 1997

Opdecamp K, Nakayama A, Nguyen MT, Hodgkinson CA, Pavan WJ, Arnheiter H.
Melanocyte development in vivo and in neural crest cell cultures: crucial dependence on the Mitf basic-helix-loop-helix-zipper transcription factor - Development  124 2377-2386 1997

Hemesath TJ, Steingrimsson E, McGill G, Hansen MJ, Vaught J, Hodgkinson CA, Arnheiter H, Copeland NG, Jenkins NA, Fisher DE.
microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family. - Genes Dev.  8 2770-80 1994

Steingrimsson E, Moore KJ, Lamoreux ML, Ferre-D'Amare AR, Burley SK, Zimring DC, Skow LC, Hodgkinson CA, Arnheiter H, Copeland NG, et al.
Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences. - Nat Genet  8 256-63 1994

Tachibana M, Perez-Jurado LA, Nakayama A, Hodgkinson CA, Li X, Schneider M, Miki T, Fex J, Francke U, Arnheiter H.
Cloning of MITF, the human homolog of the mouse microphthalmia gene and assignment to chromosome 3p14.1-p12.3. - Hum Mol Genet  3 553-557 1994

Hodgkinson CA, Moore KJ, Nakayama A, Steingrimsson E, Copeland NG, Jenkins NA, Arnheiter H.
Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein. - Cell  74 395-404 1993

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