Press Releases & News Articles: National Institute of Neurological Disorders and Stroke (NINDS) Copyright 2014, National Institute of Neurological Disorders and Stroke en Press Release Saturday Sunday NIH scientists find six new genetic risk factors for Parkinson’s A new international study has taken number crunching to the extreme. Using data from over 18,000 patients, scientists identified more than two dozen genetic risk factors involved in Parkinson’s disease, including six that had not been previously reported. The study, published in Nature Genetics, was partially funded by the National Institutes of Health (NIH) and led by scientists working in NIH laboratories. Sun, 27 Jul 2014 00:00:00 EDT Brain tumor invasion along blood vessels may lead to new cancer treatments Invading glioblastoma cells may hijack cerebral blood vessels during early stages of disease progression and damage the brain’s protective barrier, a study in mice indicates. This finding could ultimately lead to new ways to bring about the death of the tumor, as therapies may be able to reach these deadly cells at an earlier time point than was previously thought possible. Tue, 08 Jul 2014 00:00:00 EDT NIH scientists take totally tubular journey through brain cells In a new study, scientists at the National Institutes of Health took a molecular-level journey into microtubules, the hollow cylinders inside brain cells that act as skeletons and internal highways. They watched how a protein called tubulin acetyltransferase (TAT) labels the inside of microtubules. The results, published in Cell, answer long-standing questions about how TAT tagging works and offer clues as to why it is important for brain health. Wed, 11 Jun 2014 00:00:00 EDT NIH embraces bold, 12-year scientific vision for BRAIN Initiative A federal report calls for $4.5 billion in funding for brain research over the next 12 years. The long-term scientific vision of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative was presented today to National Institutes of Health Director Francis S. Collins, M.D., Ph.D., by his Advisory Committee to the Director (ACD). Dr. Collins accepted the recommendations, calling the report bold and game changing. Thu, 05 Jun 2014 00:00:00 EDT Shining a light on memory Using a flash of light, scientists have inactivated and then reactivated a memory in genetically engineered rats. The study, supported by the National Institutes of Health, is the first cause-and-effect evidence that strengthened connections between neurons are the stuff of memory. Sun, 01 Jun 2014 00:00:00 EDT Federal pain research database launched The Interagency Pain Research Portfolio (IPRP), a database that provides information about pain research and training activities supported by the federal government, has been launched by six federal agencies. Tue, 27 May 2014 00:00:00 EDT Scientists take a close-up of key pain-sensing molecule A revolutionary microscopy technique could help design better treatments for chronic pain Fri, 16 May 2014 00:00:00 EDT Worms surprise scientists with hints that stress can guard nerves Taut springs guard worm’s sensory neurons during flexing and help respond to touch, an NIH-funded study reports Fri, 16 May 2014 00:00:00 EDT Longevity gene may boost brain power Scientists showed that people who have a variant of a longevity gene, called KLOTHO, have improved brain skills such as thinking, learning and memory regardless of their age, sex, or whether they have a genetic risk factor for Alzheimer’s disease. Increasing KLOTHO gene levels in mice made them smarter, possibly by increasing the strength of connections between nerve cells in the brain. Fri, 09 May 2014 00:00:00 EDT Preliminary results show improvement in MS symptoms Combining the estrogen hormone estriol with Copaxone, a drug indicated for the treatment of patients with relapsing forms of multiple sclerosis (MS), may improve symptoms in patients with the disorder, according to preliminary results from a clinical study of 158 patients with relapsing remitting multiple sclerosis (RRMS). Tue, 29 Apr 2014 00:00:00 EDT Eavesdropping on brain cell chatter Everything we do — all of our movements, thoughts and feelings – are the result of neurons talking with one another, and recent studies have suggested that some of the conversations might not be all that private. Brain cells known as astrocytes may be listening in on, or even participating in, some of those discussions. Wed, 16 Apr 2014 00:00:00 EDT Too much protein may kill brain cells as Parkinson’s progresses Scientists may have discovered how the most common genetic cause of Parkinson’s disease destroys brain cells and devastates many patients worldwide. The study was partially funded by the National Institutes of Health’s National Institute of Neurological Disorders and Stroke (NINDS); the results may help scientists develop new therapies. Thu, 10 Apr 2014 00:00:00 EDT