Press Releases & News Articles: National Institute of Neurological Disorders and Stroke (NINDS) Copyright 2014, National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov/news_and_events/news_articles/index.htm en Press Release Saturday Sunday http://blogs.law.harvard.edu/tech/rss Scientists uncover nuclear process in the brain that may affect disease http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_glial_nuclear_pores_08172015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_glial_nuclear_pores_08172015.htm Every brain cell has a nucleus, or a central command station. Scientists have shown that the passage of molecules through the nucleus of a star-shaped cell, called an astrocyte, may play a critical role in health and disease. The study, published in the journal Nature Neuroscience, was partially funded by the National Institutes of Health (NIH). Mon, 17 Aug 2015 00:00:00 EDT PINK1 protein crucial for removing broken-down energy reactors http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_pink1_protein_08122015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_pink1_protein_08122015.htm Cells are powered by tiny energy reactors called mitochondria. When damaged, they leak destructive molecules that can cause substantial harm and eventually kill brain cells. Scientists at the NIH’s National Institute of Neurological Disorders and Stroke (NINDS) showed that a protein called PINK1 that is implicated in Parkinson’s disease is critical for helping cells get rid of dysfunctional mitochondria. Wed, 12 Aug 2015 00:00:00 EDT Neurons' broken machinery piles up in ALS http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_ALS_neurons_08122015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_ALS_neurons_08122015.htm A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If it cannot, the defective components pile up and the cell becomes sick and dies. Wed, 12 Aug 2015 00:00:00 EDT Scientists adopt new strategy to find Huntington’s disease therapies http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_HD_therapies_08072015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_HD_therapies_08072015.htm Scientists searched the chromosomes of more than 4,000 Huntington’s disease patients and found that DNA repair genes may determine when the neurological symptoms begin. Partially funded by the National Institutes of Health, the results may provide a guide for discovering new treatments for Huntington’s disease and a roadmap for studying other neurological disorders. Fri, 07 Aug 2015 00:00:00 EDT Crystal clear images uncover secrets of hormone receptors http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_clear_hormone_receptors_07312015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_clear_hormone_receptors_07312015.htm Many hormones and neurotransmitters work by binding to receptors on a cell’s exterior surface. This activates receptors causing them to twist, turn and spark chemical reactions inside cells. NIH scientists used atomic level images to show how the neuropeptide hormone neurotensin might activate its receptors. Their description is the first of its kind for a neuropeptide-binding G protein-coupled receptor (GPCR), a class of receptors involved in a wide range of disorders and the target of many drugs. Fri, 31 Jul 2015 00:00:00 EDT Futuristic brain probe allows for wireless control of neurons http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_futuristic_brain_probe_07162015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_futuristic_brain_probe_07162015.htm A study showed that scientists can wirelessly control the path a mouse walks with just a press of a button. Researchers at the Washington University School of Medicine, St. Louis, and University of Illinois, Urbana-Champaign, created a remote controlled, next-generation tissue implant that allows neuroscientists to inject drugs and shine lights on neurons deep inside the brains of mice. Thu, 16 Jul 2015 00:00:00 EDT Normal neuronal firing may spark brain tumor growth http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_sparking_brain_tumors_06162015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_sparking_brain_tumors_06162015.htm Using human brain tumor samples, scientists have discovered that normal patterns of nerve cell firing may enhance the growth of cancer cells. They also found that, neuroligin-3 (NLGN3), a gene known to be important for brain cell communication, may influence tumor growth and patient survival, making it a potential new target for therapy. The study, published in Cell, was partially funded by the National Institutes of Health (NIH). Tue, 16 Jun 2015 00:00:00 EDT Progesterone does not significantly improve outcome after traumatic brain injury http://www.ninds.nih.gov/news_and_events/news_articles/news_article_progesterone_06152015.htm http://www.ninds.nih.gov/news_and_events/news_articles/news_article_progesterone_06152015.htm Results of a phase 3 randomized, placebo-controlled clinical trial suggest that progesterone may not significantly improve outcomes in patients who have suffered a moderate to severe traumatic brain injury. Tue, 16 Jun 2015 00:00:00 EDT NIH Names Walter J. Koroshetz, M.D. Director of the National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_director_06112015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_director_06112015.htm National Institutes of Health Director Francis S. Collins, M.D., Ph.D. announced today the selection of Walter J. Koroshetz, M.D., as the Director of the National Institute of Neurological Disorders and Stroke (NINDS). He has served as Acting Director of the NINDS since October, 2014. Thu, 11 Jun 2015 00:00:00 EDT Scientists create mice with a major genetic cause of ALS and FTD http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_ALS_FTD_05222015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_ALS_FTD_05222015.htm Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that exhibits the symptoms and neurodegeneration associated with the most common genetic forms of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, Lou Gehrig’s disease), both of which are caused by a mutation in the a gene called C9ORF72. Fri, 22 May 2015 00:00:00 EDT A SMARTer approach to stroke care http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_SMART_05132015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_SMART_05132015.htm Time is critical when it comes to stroke: early treatment is associated with better outcomes. According to the Screening with MRI for Accurate and Rapid stroke Treatment (SMART) study, small changes in quality improvement procedures enabled clinicians to use MRI scans to diagnose stroke patients before giving acute treatment, within 60 minutes of hospital arrival. MRI scans provide detailed images but take longer to complete than CT scans, which are commonly used in most centers. Wed, 13 May 2015 00:00:00 EDT Scientists unravel the mystery of the tubulin code http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_tubulin_code_05122015.htm http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_tubulin_code_05122015.htm Driving down the highway, you encounter ever-changing signs— speed limits, exits, food and gas options. Seeing these roadside markers may cause you to slow down, change lanes or start thinking about lunch. In a similar way, cellular structures called microtubules are tagged with a variety of chemical markers that can influence cell functions. The pattern of these markers makes up the “tubulin code” and according to a paper published in Cell, scientists at NIH’s National Institute of Neurological Disorders and Stroke (NINDS) have uncovered the mechanism behind one of the main writers of this code, tubulin tyrosine ligase-7 (TTLL7). Tue, 12 May 2015 00:00:00 EDT