Press Releases & News Articles: National Institute of Neurological Disorders and Stroke (NINDS) Copyright 2015, National Institute of Neurological Disorders and Stroke en Press Release Saturday Sunday Study shows how fruit flies beat the heat (and cold) Humans aren’t the only ones that take shelter when the weather turns unpleasant. A team of researchers at Northwestern University’s Department of Neurobiology has mapped the neural circuits that allow flies to avoid uncomfortable temperatures. Mon, 23 Nov 2015 00:00:00 EST Batten disease may benefit from gene therapy In a study of dogs, scientists showed that a new way to deliver replacement genes may be effective at slowing the development of childhood Batten disease, a rare and fatal neurological disorder. Wed, 11 Nov 2015 00:00:00 EST Scientists identify main component of brain repair after stroke Looking at brain tissue from mice, monkeys and humans, scientists have found that a molecule known as growth and differentiation factor 10 (GDF10) is a key player in repair mechanisms following stroke. The findings suggest that GDF10 may be a potential therapy for recovery after stroke. The study, published in Nature Neuroscience, was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. Wed, 28 Oct 2015 00:00:00 EDT An itch you just can’t scratch Everyone knows the best way to suppress an itch is to scratch it, but for people who suffer from skin diseases like eczema, no amount of scratching can bring relief. Fortunately, help may be on the way. Scientists from the Buck Institute for Research on Aging and the University of California, Berkeley have identified a pair of proteins responsible for chronic itching. The study, published in Neuron and partially funded by the NIH’s National Institute of Neurological Disorders and Stroke (NINDS), may lead to treatments that can stop an itch at its source. Tue, 27 Oct 2015 00:00:00 EDT Study in mice shows how brain ignores distractions In a study of mice, scientists discovered that a brain region called the thalamus may be critical for filtering out distractions. The study, published in Nature and partially funded by the National Institutes of Health, paves the way to understanding how defects in the thalamus might underlie symptoms seen in patients with autism, attention deficit hyperactivity disorder (ADHD), and schizophrenia. Wed, 21 Oct 2015 00:00:00 EDT Nuclear transport problems linked to ALS and FTD Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell’s nucleus, or command center where most of its DNA is stored. Fri, 16 Oct 2015 00:00:00 EDT NIH invests $85 million for BRAIN Initiative research$85-million-for-BRAIN-Initiative-Research.htm$85-million-for-BRAIN-Initiative-Research.htm The National Institutes of Health announced its second wave of grants to support the goals of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, bringing the NIH investment to $85 million in fiscal year 2015. Thu, 01 Oct 2015 00:00:00 EDT Dormant viral genes may awaken to cause ALS Scientists at the National Institutes of Health (NIH) discovered that reactivation of ancient viral genes embedded in the human genome may cause the destruction of neurons in some forms of amyotrophic lateral sclerosis (ALS). Wed, 30 Sep 2015 00:00:00 EDT Scientists uncover nuclear process in the brain that may affect disease Every brain cell has a nucleus, or a central command station. Scientists have shown that the passage of molecules through the nucleus of a star-shaped cell, called an astrocyte, may play a critical role in health and disease. The study, published in the journal Nature Neuroscience, was partially funded by the National Institutes of Health (NIH). Mon, 17 Aug 2015 00:00:00 EDT PINK1 protein crucial for removing broken-down energy reactors Cells are powered by tiny energy reactors called mitochondria. When damaged, they leak destructive molecules that can cause substantial harm and eventually kill brain cells. Scientists at the NIH’s National Institute of Neurological Disorders and Stroke (NINDS) showed that a protein called PINK1 that is implicated in Parkinson’s disease is critical for helping cells get rid of dysfunctional mitochondria. Wed, 12 Aug 2015 00:00:00 EDT Neurons' broken machinery piles up in ALS A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If it cannot, the defective components pile up and the cell becomes sick and dies. Wed, 12 Aug 2015 00:00:00 EDT Scientists adopt new strategy to find Huntington’s disease therapies Scientists searched the chromosomes of more than 4,000 Huntington’s disease patients and found that DNA repair genes may determine when the neurological symptoms begin. Partially funded by the National Institutes of Health, the results may provide a guide for discovering new treatments for Huntington’s disease and a roadmap for studying other neurological disorders. Fri, 07 Aug 2015 00:00:00 EDT