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NIH nearly doubles investment in BRAIN Initiative research
Thursday, Oct 13, 2016
The National Institutes of Health announced its third round of grants to support the goals of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, bringing NIH’s total fiscal year 2016 investment to just over $150 million.

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NIH-supported NeuroBioBank joins Autism BrainNet in brain donation initiative
Tuesday, Nov 17 2015
The National Institute of Mental Health (NIMH) has signed an agreement to establish a collaborative, nationwide effort for the collection, storage, and distribution of postmortem human brain tissue for the benefit of autism research. The agreement with Foundation Associates LLC will coordinate the efforts of two independent networks of human brain tissue repositories, the National Institutes of Health NeuroBioBank (NBB) and the Autism BrainNet (ABN).

GluCEST MRI

New brain imaging technique identifies previously undetected epileptic seizure sites
Thursday, Nov 12 2015
People with epilepsy experience uncontrolled seizures that can impair quality of life and cause stigma that leads to social isolation. The neurological condition can limit some activities most people take for granted, such as sustaining work or operating a vehicle. Researchers at the University of Pennsylvania and funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have developed a non-invasive brain imaging technique for a class of patients whose epilepsy symptoms do not respond to drug treatment and who would otherwise be poor candidates for seizure-relieving surgeries.

NINDS congratulates Beth Stevens, winner of a 2015 MacArthur Foundation Fellowship

NINDS congratulates Beth Stevens, winner of a 2015 MacArthur Foundation Fellowship
Monday, Sep 28, 2015
On September 28, 2015, Dr. Stevens was awarded a 2015 MacArthur Foundation Fellowship for her work on microglia and brain development. NINDS congratulates Dr. Stevens.

Landmark NIH study shows intensive blood pressure management may save lives

Landmark NIH study shows intensive blood pressure management may save lives
Friday, Sep 11, 2015
More intensive management of high blood pressure, below a commonly recommended blood pressure target, significantly reduces rates of cardiovascular disease, and lowers risk of death in a group of adults 50 years and older with high blood pressure. This is according to the initial results of a landmark clinical trial sponsored by the National Institutes of Health called the Systolic Blood Pressure Intervention Trial (SPRINT) (NIH).

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NIH and CDC Announce Grantees for the Sudden Death in the Young Registry
Wednesday, Oct 15, 2014
The NIH and CDC announce awards to ten grantees for the Sudden Death in the Young Registry. Six are current or former grantees from the Sudden Unexpected Infant Death (SUID) Registry: Georgia, Michigan, Minnesota, New Hampshire, New Jersey, and Wisconsin. Four are new grantees: Delaware, Tennessee, the city of San Francisco and the Tidewater region of Virginia. Grants were awarded on September 30, 2014. After a period of training and preparation, the grantees will begin reviewing cases in January 2015.

Movies reveal cause of death from cerebral malaria

Raising the curtain on cerebral malaria’s deadly agents
Tuesday, Dec 6, 2016
Using state-of-the-art brain imaging technology, scientists at the National Institutes of Health filmed what happens in the brains of mice that developed cerebral malaria (CM). The results, published in PLOS Pathogens, reveal the processes that lead to fatal outcomes of the disease and suggest an antibody therapy that may treat it.

Tauopathy-induced Neuronal Degeneration

Untangling a cause of memory loss in neurodegenerative diseases
Tuesday, Oct 11, 2016
Tauopathies are a group of neurodegenerative disorders, including Alzheimer’s disease that are characterized by the deposition of aggregates of the tau protein inside brain cells. A new study reveals that the cutting of tau by an enzyme called caspase-2 may play a critical role in the disordered brain circuit function that occurs in these diseases. Of interest, the culprit tau fragment identified in this study is actually resistant to forming aggregates, and it causes a disturbance in memory function in animal models before brain cell loss occurs.

Targeting cardiovascular disease risk factors may be important across a lifetime
Wednesday, Oct 5, 2016
New findings suggest that all adults, including those over 65, should be mindful of risk factors for cardiovascular disease. The results, published in the Journal of the American Geriatric Society, are part of the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, which looks at stroke incidence in approximately 30,000 individuals. The REGARDS study is funded by the National Institutes of Health’s National Institute of Neurological Disorders and Stroke (NINDS).

Propagating toxic ɑ-synuclein fibrils

Researchers find a gap in the brain’s firewall against Parkinson’s disease
Friday, Sep 30, 2016
In a study in mice, researchers found that they could reduce the progression of the toxic aggregates of α-synuclein that are found in the brains of Parkinson’s disease patients. The results suggest that a protein called lymphocyte-activation gene 3 (LAG3) plays a role in transmitting α-synuclein aggregates from one brain cell to another and could provide a possible target to slow the progression of Parkinson’s disease. The study, published in Science, was partially funded by the National Institutes of Health’s National Institute of Neurological Disorders and Stroke (NINDS).

Unlocking the mysteries of our senses

“Sixth sense” may be more than just a feeling
Friday, Sep 23, 2016
With the help of two young patients with a unique neurological disorder, an initial study by scientists at the National Institutes of Health suggests that a gene called PIEZO2 controls specific aspects of human touch and proprioception, a “sixth sense” describing awareness of one’s body in space. Mutations in the gene caused the two to have movement and balance problems and the loss of some forms of touch. Despite their difficulties, they both appeared to cope with these challenges by relying heavily on vision and other senses.


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Researchers find essential brain circuit in visual development
Monday Aug 26, 2013
A study in mice reveals an elegant circuit within the developing visual system that helps dictate how the eyes connect to the brain. The research, funded by the National Institutes of Health, has implications for treating amblyopia, a vision disorder that occurs when the brain ignores one eye in favor of the other.

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