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Small Business Funding Opportunities

Funding Opportunities

The NINDS accepts a broad range of small business applications that are significant, innovative, and relevant to its mission. Small businesses are invited to apply for NINDS funding through the Omnibus Solicitations (PA 14-071 for SBIR; PA 14-072 for STTR) and the majority of our applications come through this general announcement. In addition, program staff will also solicit applications in specific program areas. Some specific program announcements include:

        Program Announcements

  • PA-11-347: NINDS SBIR Technology Transfer (SBIR)
  • PAR-12-054: Advanced Neural Prosthetics Research and Development (U44) 
  • PAR-12-072 /PAR-12-073: NINDS Exploratory Clinical Trials for Small Business (STTR/SBIR)
  • PA-12-149/PA-12-150: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp)
  • PA-12-189/PA-12-190: Advanced Tools and Technologies for Cerebrospinal Fluid Shunts (SBIR/STTR)
  • PA-13-140: Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR)
  • PAR-13-090/PAR-13-191: Safe and Effective Instruments and Devices for Use in Neonatal and Pediatric Care Settings (SBIR/STTR)
  • PAR-14-088: Direct Phase II SBIR Grants to Support Biomedical Technology Development (SBIR)
  • PA-14-154/PAR-14-157: Early Stage Development of Technologies in Biomedical Computing, Informatics, and Big Data Science (SBIR/STTR)
  • PAR-14-252: StrokeNet Small Business Innovation Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U44)
  • PAR-14-208: NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Exploratory Clinical Trials and Clinical Research (R44)
  • PAR-14-209: NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Pre-Clinical Research (R44)
  • PAR-14-265: NINDS Direct Phase II SBIR Grants to Support Exploratory Clinical Trials (R44)
  • PAR-14-287: NINDS CREATE Bio Discovery Track: Optimization in Preparation for Development of Biotechnology Products and Biologics (U44)
  • PAR-14-289: NINDS CREATE Bio Development Track: Preclinical and Early-phase Clinical Development for Biotechnology Products and Biologics (U44)
  • PAR-14-300: NINDS CREATE Devices: Translational and Clinical Studies to Inform Final Device Design (U44)
  • PAR-14-299: NINDS CREATE Devices: Translational and Early Feasibility Studies on the Path to Pre-Market Approval (PMA) or Humanitarian Device Exemption (HDE) (U44)
  • PAR-14-296: NINDS CREATE Devices: Translational and Clinical Studies on the Path to 510(k) (U44)
  • PAR-14-292: Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44)


  • NOT-NS-11-018: NINDS Policy for the Requirement of Authorization from the Food and Drug Administration (FDA) to use an Investigational Drug, Biologic Product or Device in a Clinical Trial Prior to Submission of an Application
  • NOT-OD-13-003: Commercialization Assistance Program for SBIR/STTR Phase II Awardees
  • NOT-OD-13-071: HHS Reissues PHS 2013-02 SBIR and STTR Omnibus Grant Solicitations Implementing Venture Capital Provision and SBA Company Registry Requirement of the SBIR/STTR Reauthorization Act of 2011
  • NOT-OD014-048: NIH Implements Option for Applicants to Switch between the SBIR/STTR programs and the SBIR Direct to Phase II pilot of the SBIR/STTR Reauthorization Act of 2011
  • NOT-OD-14-074: NIH Policy on Resubmission Applications
  • NOT-OD-15-003: NIH Offers Niche Assessment Program to SBIR and STTR Phase I Awardees
  • NOT-OD-15-036: Notice To Extend PA-14-071 "PHS 2014-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])"
  • NOT-OD-15-037: Notice To Extend PA-14-072 "PHS 2014-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])"
  • NOT-OD-15-038: HHS Changes Standard Due Dates for SBIR/STTR Grant Applications

More details about these opportunities can be found in the NIH Guide for Grants and Contracts.

Last updated December 18, 2014