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Small Business Funding Opportunities

Funding Opportunities

The NINDS accepts a broad range of small business applications that are significant, innovative, and relevant to its mission. Small businesses are invited to apply for NINDS funding through the Omnibus Solicitations (PA 14-071 for SBIR; PA 14-072 for STTR) and the majority of our applications come through this general announcement. In addition, program staff will also solicit applications in specific program areas. Some specific program announcements include:

        Program Announcements

  • PA-11-347: NINDS SBIR Technology Transfer (SBIR)
  • PAR-11-345: NeuroNEXT Small Business Innovation in Clinical Trials (U44) 
  • PAR-12-054: Advanced Neural Prosthetics Research and Development (U44) 
  • PAR-12-072 /PAR-12-073: NINDS Exploratory Clinical Trials for Small Business (STTR/SBIR)
  • PA-12-149/PA-12-150: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp)
  • PA-12-189/PA-12-190: Advanced Tools and Technologies for Cerebrospinal Fluid Shunts (SBIR/STTR)
  • PA-13-140: Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR)
  • PAR-13-090/PAR-13-191: Safe and Effective Instruments and Devices for Use in Neonatal and Pediatric Care Settings (SBIR/STTR)
  • PAR-14-088: Direct Phase II SBIR Grants to Support Biomedical Technology Development (SBIR)
  • PA-14-154/PAR-14-157: Early Stage Development of Technologies in Biomedical Computing, Informatics, and Big Data Science (SBIR/STTR)
  • PAR-14-252: StrokeNet Small Business Innovation Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U44)
  • PAR-14-208: NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Exploratory Clinical Trials and Clinical Research (R44)
  • PAR-14-209: NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Pre-Clinical Research (R44)
  • PAR-14-261: Innovation Corps (I-CorpsTM) Team Training Pilot Program of NIH Phase 1 SBIR and STTR Grantees (Admin Supp)
  • PAR-14-265: NINDS Direct Phase II SBIR Grants to Support Exploratory Clinical Trials (R44)
  • PAR-14-287: NINDS CREATE Bio Discovery Track: Optimization in Preparation for Development of Biotechnology Products and Biologics (U44)
  • PAR-14-289: NINDS CREATE Bio Development Track: Preclinical and Early-phase Clinical Development for Biotechnology Products and Biologics (U44)


  • NOT-NS-11-018: NINDS Policy for the Requirement of Authorization from the Food and Drug Administration (FDA) to use an Investigational Drug, Biologic Product or Device in a Clinical Trial Prior to Submission of an Application
  • NOT-OD-12-146: SBIR/STTR Niche Assessment Program for Phase I Awardees
  • NOT-OD-13-003: Commercialization Assistance Program for SBIR/STTR Phase II Awardees
  • NOT-OD-13-071: HHS Reissues PHS 2013-02 SBIR and STTR Omnibus Grant Solicitations Implementing Venture Capital Provision and SBA Company Registry Requirement of the SBIR/STTR Reauthorization Act of 2011
  • NOT-OD-13-116: New Program Certifications Required for SBIR and STTR Awards
  • NOT-OD014-048: NIH Implements Option for Applicants to Switch between the SBIR/STTR programs and the SBIR Direct to Phase II pilot of the SBIR/STTR Reauthorization Act of 2011
  • NOT-OD-14-074: NIH Policy on Resubmission Applications
  • NOT-NS-14-021: Notice of Intent to Publish a Funding Opportunity Announcement for the "Blueprint Neurotherapeutics Network (BPN): SBIR Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44)"

More details about these opportunities can be found in the NIH Guide for Grants and Contracts.

Last updated July 22, 2014