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Notices, Policy Announcements and Other Information:
Institutional National Research Service Award (NRSA) Training Grants
Individual National Research Service Award (NRSA) Fellowships
Mentored Research Career Development Awards:
Independent Scientist Research Career Awards:
Academic Research Enhancement Award (AREA Grants):
Postdoctoral Fellowships
F05 - International Neuroscience Fellowship Program
The goal of the International Neuroscience Fellowship is to advance the training of qualified foreign neuroscientists by
enhancing their basic or clinical research skills in a research setting in the U.S. Eligible individual applicants include
non-immigrant foreign scientists who are currently residing outside the U.S. The applicant must have a doctoral or equivalent
degree, an endorsement from their home institution, and a guaranteed appointment in an institution in their home country upon
completion of the fellowship. Applicants must have a sponsor in the U.S. who is affiliated with an eligible U.S. organization
and must be proficient in English. Preference will be given to applicants from low- to middle-income countries.
F32 - Ruth L. Kirschstein National Research Service Awards for Individual Postdoctoral Fellows
Individual National Research Service Awards (F32) are made to applicants seeking postdoctoral research training in the basic
or clinical neurological sciences. Before beginning the proposed fellowship, an applicant must earn a doctoral degree. In
addition to biomedical research training, the proposed study must include an opportunity to conduct research. The training
plan should provide an opportunity for research scientists and clinicians to broaden their scientific background or to extend
their potential for research in health-related areas. Training areas are generally the same as those identified earlier for
institutional training grants. Before formally submitting their applications, prospective fellows must arrange for an appointment
to an appropriate institution and acceptance by a sponsor who will supervise the training and research experience. The application
must document that staff and facilities are available to provide a high-quality training opportunity. The application should
emphasize opportunities for research training and broadening scientific competence.
F32 - Ruth L. Kirschstein National Research Service Awards for Interdisciplinary Individual Postdoctoral Fellows for Training in Neurodegeneration Research
This postdoctoral fellowship program is an Initiative of the NIH Blueprint for Neuroscience Research. The purpose of this program is to provide interdisciplinary postdoctoral training in neurodegeneration research. The training plan should include didactic training, research, and collaborative activities. Applicants must also outline a plan to incorporate faculty and resources from different departments that may be historically distinct but may provide insight for understanding and treating neurodegenerative disorders.
F32 - Ruth L. Kirschstein National Research Service Awards for Postdoctoral Fellowships in Muscle Disease Research
This postdoctoral fellowship program is designed to support research training to promising applicants with the potential to become productive investigators in basic, translational and clinical research of muscular dystrophy and other muscle diseases.
K01 - Mentored Research Scientist Development Award
The NINDS has three separate programs under the aegis of the Mentored Research Scientist Development Award (MRSDA): A. NINDS Mentored Research Scientist Development Awards in Translational Research, B. Career Development Award for Minority Scholars in Neuroscience, and C. Re-Entry Into the Neurological Sciences Program. A description of each program follows.
K08 - Mentored Clinical Scientist Research Career Development Award
The NINDS participates in three distinct programs utilizing the K08 mechanism: A. Mentored Clinical Scientist Research Career Development Award, B. NINDS Mentored Clinical Scientist Development Awards in Translational Research, and C. Mentored Clinical Investigator Career Development Awards in Muscle Disease Research. A description of each program follows.
K12 - Neurological Sciences Academic Development Award (NSADA)
As of August 2, 2006, the National Institute of Neurological Disorders and Stroke has suspended this program. No new or amended applications to PAR-03-103 will be accepted. NINDS may re-issue this program announcement in the future. For more information, see NOT-NS-06-015.
K22 - NINDS Career Transition Award
As of March 2, 2006, no more applications were accepted for the K22 Program. Fellows who were considering this mechanism should consider the K99/R00 Pathway to Independence Award.
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K23 - Mentored Patient-Oriented Research Career Development Award
The Mentored Patient-Oriented Research Career Development Award (K23) was created to support the career development of investigators
who have made a commitment to focus their research endeavors on patient-oriented research. For the purposes of this award,
patient-oriented research is defined as research conducted with human subjects (or on material of human origin such as tissues,
specimens, and cognitive phenomena) for which an investigator directly interacts with human subjects. This area of research
includes: 1) mechanisms of human disease; 2) therapeutic interventions; 3) clinical trials; and 4) the development of new
technologies. This mechanism provides support for a period of supervised study and research for clinically trained professionals
(MD or equivalent) who have the potential to develop into productive clinical investigators focusing on patient-oriented research.
The project period may be 3-5 years. Candidates must devote a minimum of 75% of full-time professional effort in research
career development and clinical research activities.
Special Note: To accommodate neurosurgeons, who need significant clinical activity to maintain their surgical skills, NINDS
will accept 50% time commitment to the award.
Salary and Research Costs: : NINDS will provide up to $85,000 of the awardees salary per year, and up to $50,000 per year toward research costs. K23
award recipients are encouraged to apply for independent research awards while the K award is active, and should consult with
the Director of Training and Career Development for budget guidance in this process.
Institutional Support: Please pay careful attention to specific issues that must be addressed in a statement of institutional support for K08 and K23 awards.
K23 - Mentored Clinical Investigator Career Development Awards in Muscle Disease Research
The purpose of this program is to encourage clinical investigators with a diverse range of specialties to apply their expertise to patient-oriented research in muscle disease pathogenesis and treatment. Prior experience in muscle disease or muscle biology research is not necessary, provided that the mentor has appropriate expertise. For the purposes of this award, patient-oriented research is defined as research conducted with human subjects or material for which an investigator directly interacts with human subjects. Possible targets of investigation are mechanisms of muscle disease, therapeutic interventions, clinical trials, and development of new technologies, as well as epidemiologic, behavioral, outcomes or health services research. This award will provide “protected time” for investigators to become familiar with the field of muscle disease research and develop innovative approaches for studying this category of diseases, which includes but is not limited to Duchenne, myotonic and facioscapulohumeral, malignant hyperthermia, muscle wasting disorders, inflammatory myopathies, and genetic muscle diseases. The award supports a 3-5 year period of supervised basic or clinical research, during which the candidate must devote a minimum of 75% of his or her time and effort to the proposed research and career development activities.
Special Note: To accommodate neurosurgeons, who need significant clinical activity to maintain their surgical skills, NINDS will accept 50% time commitment to the award.
Salary and Research Costs: : NINDS will provide up to $85,000 of the awardees salary per year, and up to $50,000 per year toward research costs. K23 award recipients are encouraged to apply for independent research awards while the K award is active, and should consult with the Director of Training and Career Development for budget guidance in this process.
Institutional Support: Please pay careful attention to specific issues that must be addressed in a statement of institutional support for K08 and K23 awards.
K25 - Mentored Quantitative Research Career Development Award
As of August 22, 2006, the eligibility criteria for this program have changed. See the Notice for details.
The purpose of the Mentored Quantitative Research Career Development Award (K25) is to support the career development of investigators with quantitative scientific and engineering backgrounds outside of biology or medicine who have made a commitment to focus their research endeavors on behavioral and biomedical research (basic or clinical). Examples of quantitative scientific and technical backgrounds outside of biology or medicine considered appropriate for this award include, but are not limited to: mathematics, statistics, computer science, informatics, physics, chemistry and engineering. Candidates for this award must have demonstrated research interests with an advanced degree in a quantitative area of science or engineering (e.g., M.S.E.E., PhD, D.Sc.). They must identify a mentor with extensive behavioral or biomedical research experience, and must devote at least 75% full-time professional effort conducting research career development and basic or clinical research.
K99/R00 - NIH Pathway to Independence (PI) Award
The Pathway to Independence Award is uniquely designed to facilitate the transition of outstanding postdoctoral candidates from mentored to independent research positions. The award contains two components, a mentored (K99) phase that can last up to 2 years and an independent (R00) phase, which will have a duration of 3 years. The objective of the program is to facilitate research independence earlier in an investigator's career. Investigators complete supervised research, and apply for an independent research faculty position, during the mentored phase of the award. Activation of the independent award phase is administrative, and is contingent upon the investigator securing an independent research position. Eligible candidates will have no more than 5 years of postdoctoral research at the time of application (initial or amended). In addition, eligible applicants will currently be in a mentored postdoctoral position, regardless of title. Review the NIH definition of a postdoctoral scholar. Award recipients are expected to obtain R01 support during the independent phase of the award.Salary and Research Costs: For mentored candidates in an extramural institution, NINDS will provide up to $50,000 per year for salary support (up to $85,000 per year for applicants with an M.D. degree), plus fringe, and up to $20,000 for research support costs. Budget details for mentored candidates in the NIH intramural program will be negotiated with the sponsoring laboratory and will be consistent with offers to scientists in comparable positions.
K02 - Independent Scientist Award
The intent of the Independent Scientist Award (K02) is to support health professionals who are committed to a career in neuroscience research and who have recently achieved independent scientist status. This program normally follows a K08 or K23 award and supports the continued career development of independent clinician-scientists so that they can be more successful in obtaining an R01 or equivalent grant. The award provides salary and research costs for the first three years, and continued salary support for years four and five, with the last two years of support contingent on successful competition for an R01 or equivalent award. In contrast to requirements of other institutes, applicants are not eligible for this award if they have a major, independent, peer-reviewed research grant (R01, subproject on a P01, or equivalent) prior to receiving the K02 award. Awardees are encouraged to apply for R01 support at any time after they’ve received the K02 award.
The candidates must hold a clinical doctoral degree, have completed postgraduate clinical training prior to application, and hold a primary appointment in a clinical department. The candidate must also devote a minimum of 75% effort to the proposed award activities.
Special Note: To accommodate neurosurgeons, who need significant clinical activity to maintain their surgical skills, NINDS will accept 50% time commitment to the award.
Salary and Research Costs: Salary and Research Costs: In years 1 - 3 of the K02 award, NINDS will provide up to $95,000 of the awardee's salary per
year, plus the applicable fringe benefit rate, plus up to $50,000 per year toward research costs. Once an applicant receives
an R01 or equivalent award, the applicant may obtain up to 80% of their institutional base salary from the K02, commensurate
with their effort on the K02. Once an R01 or equivalent is obtained, research costs will no longer be provided through the
K02 award.
For a more detailed explanation of the K02 award structure, see the change in policy guidance for this mechanism.
For questions regarding this new funding strategy for K02 awards, contact the Director of Training and Career Development.
Institutional Support: Please pay careful attention to specific issues that must be addressed in a statement of institutional support for the K02.
K18 - Short-Term Interdisciplinary Career Enhancement Awards for Neurodegeneration Research
As of November 8, 2006, the competition for this program is closed. No new or amended applications to RFA-DC-07-005 will be accepted. For current funding opportunities offered through the NIH Blueprint for Neuroscience Research, see the NIH Blueprint website.
K24 - Midcareer Investigator Award in Patient-Oriented Research
The Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support for clinicians to allow them protected
time to devote to patient-oriented research and to act as mentors for beginning clinical investigators. For the purposes of
this award, patient-oriented research is defined as research conducted with human subjects (or on material of human origin
such as tissues, specimens, and cognitive phenomena) for which an investigator directly interacts with human subjects. This
area of research includes: 1) mechanisms of human disease; 2) therapeutic interventions; 3) clinical trials; and 4) the development
of new technologies. The target candidates are outstanding clinical scientists engaged in patient-oriented research who are
generally within 15 years of their specialty training, who can demonstrate the need for a period of intensive research focus
as a means of enhancing their clinical research careers, and who are committed to mentoring the next generation of clinical
investigators focusing on patient-oriented research. The project period may be up to 5 years. Awards are renewable for one
additional 5-year period if the candidate still meets the stated requirements. Candidates for this award must have a clinical
degree (e.g., MD or equivalent), and must devote between 25-50% effort conducting patient-oriented research and mentoring
more junior colleagues. Applicants must have independent research support at the time of application for this program, and
recipients of this award are required to hold independent research support, either Federal or private, during the period of
this award.
Salary and Research Costs: The NINDS will provide salary in accordance with NIH policy: Salary Limitation on Grants, Cooperative Agreements and Contracts. NINDS does not provide funds through the K24 for research, as these costs are provided for by the applicant's RPG funding.
NINDS will provide up to $30,000 for costs associated with the development and implementation of mentoring activities. Applicants
requesting costs for mentoring expenses must provide a detailed justification for the request.
R15 - Academic Research Enhancement Award (AREA)
Last updated April 29, 2008