NIH encourages applications for assay development for high-throughput molecular screening.
This is an NIH Roadmap initiative. The NIH Roadmap is an innovative approach to accelerate fundamental discovery and translate that knowledge into effective prevention strategies and new treatments.
This announcement supports the discovery of new molecular probes for investigating biological function by funding the development and adaptation of biological assays for use in automated high-throughput screening (HTS) projects. These HTS-ready assays then can be screened by the Molecular Libraries Production Centers Network to identify biologically active compounds in a large library of small molecule chemical structures. HTS is the automated, simultaneous testing of thousands of distinct chemicals in models of biological mechanisms. The immense potential of HTS to impact the understanding of biological mechanisms is largely untapped because access to automated screening facilities and large compound libraries is limited in academic, government, and non-profit research sectors.
Application Due Date: October 29, 2010
Potential applicants should contact Dr. Mark Scheideler, program director, Offi ce of Translational Research, NINDS, at 301-496-1779 or email@example.com. For more information visit http://grants.nih. gov/grants/guide/pa-files/PAR-10-182.html.