NINDS is seeking persons with primary progressive multiple sclerosis for participation in a research study on the efficacy of an experimental oral drug. The study will involve a 1-year baseline period after which participants will receive the study medication or placebo (an inactive substance) for 2 years. Medical evaluations, MRIs, and bloodwork will be performed at scheduled intervals during the 3-year study.
Participants must be 18 to 55 years of age with a diagnosis of primary progressive multiple sclerosis and not taking any immunomodulatory drugs.
The study will take place at the NIH Clinical Center in Bethesda, MD. Visits will last 2-5 hours each and will be every month for the first 3 months and then every 6 months for the remainder of the study. There is no cost for participation or for any study-related tests. Transportation reimbursement will be provided.
For more information, contact Joan Ohayon at 301-496-0064. Please refer to study number 09-N-0197.