The National Institute of Neurological Disorders and Stroke (NINDS) and the National Institute on Aging (NIA) invite grant applications for research on the mechanisms of transmission and dissemination of transmissible spongiform encephalopathies (TSEs).
TSEs or “prion diseases” are neurodegenerative disorders that can lead to dementia, motor dysfunction, and, eventually, death. Prion diseases include bovine spongiform encephalopathy in cattle, scrapie in sheep, chronic wasting disease in mule deer and elk, and kuru and Creutzfeldt-Jakob disease in humans. Little is known about the natural spread of TSEs within affected populations. Understanding the natural pathways by which TSEs arise and are transmitted may be critical for protecting populations at risk for acquiring these diseases.
For more information, potential applicants should contact Dr. Michael Nunn, Program Director, Neural Environment Cluster, NINDS; telephone: 301-496-1431; e-mail: mn52e@nih.gov. For a more detailed description of this announcement, visit http://grants.nih.gov/grants/guide/pa-files/PA-07-199.html.