The National Institute of Neurological Disorders and Stroke (NINDS) invites grant applications for research on axonal damage in multiple sclerosis (MS) and strategies for protection and repair.
MS is the second most common neurological disorder leading to disability in young adults, surpassed only by trauma. The disease is characterized by chronic inflammation and demyelination of the central nervous system (CNS) that over time may result in neurodegeneration. While axonal damage and neuronal cell death are likely to be the major cause of disability in the later, progressive phase of MS, new evidence suggests that even at early stages severance of nerve axons may occur and lead to irreparable nerve damage. Currently available therapies do not appear to significantly impact this tissue loss.
For more information, potential applicants should contact Dr. Ursula Utz, Program Director, Neural Environment Cluster, NINDS; telephone: 301-496-1431; e-mail: firstname.lastname@example.org. For a more detailed description of this announcement, visit http://grants.nih.gov/grants/guide/pa-files/PAS-07-193.html.