The National Institutes of Health (NIH) solicits assays for high-throughput screening (HTS) in the molecular libraries screening centers network (MLSCN).
This program announcement is an NIH Roadmap Initiative. The NIH Roadmap is an innovative approach to accelerate fundamental discovery and translate that knowledge into effective prevention strategies and new treatments. All NIH institutes and centers participate in Roadmap Initiatives.*
The NIH is committed to a major effort to broaden access to HTS technologies and the information produced by these approaches for researchers in academia, government, and non-profit institutions. The objective of this initiative is to invite HTS assay applications to support the MLSCN. The goal of the network is to optimize and implement a variety of innovative biological, biophysical, and cell-based assays for biological targets or processes for which there are limited selective and potent small molecule modulators available to the public.
The MLSCN will provide the following services for assays selected for implementation in this program: assay implementation, compound library, HTS screening, optimization chemistry, and HTS informatics. Assay applications will be evaluated based on: readiness for or adaptability to HTS; assay performance and robustness; and diversity of assay types.
For more information, potential applicants should contact Dr. Ingrid Li, Molecular Libraries Assay Access Project Team, NIH Molecular Libraries and Imaging Roadmap, NIMH, 6001 Executive Boulevard, Room 7185, Bethesda, MD 20892; telephone: 301-443-5288; fax: 301-402-4740; e-mail: email@example.com.
*For a full list of supporting NIH components and a more detailed description of this announcement, please visit the NIH web site at: http://grants.nih.gov/grants/guide/pa-files/PAR-06-259.html. For more information on the NIH Roadmap, please visit the web site at: http://nihroadmap.nih.gov/.