The National Institute of Neurological Disorders and Stroke (NINDS), the National Institute on Aging (NIA), and the National Institute of Nursing Research (NINR) invite grant applications for research on the cognitive sequelae of Parkinson's disease (PD). This announcement is supported by 2 funding mechanisms: R03 and R21.*
PD is commonly viewed as a motor disorder, however, it also affects thinking, reasoning, learning, processing speed, and other cognitive abilities. The cognitive changes seen in people with PD are less understood and studied than the motor symptoms.
Areas of research interest include, but are not limited to: basic molecular or cellular studies of potential drugs or other treatments that could address cognitive impairments in PD; behavioral and physiological characterization of models based on the new molecular understanding of synuclein, parkin, and other proteins involved in the pathogenic processes of neurodegenerative disorders; development of relevant animal models for studying cognitive deficits in PD; preclinical studies of cognitive tests and paradigms in animal models of PD; studies of neuroprotective or other agents in animal models of PD with induced cognitive deficits; investigations of the relationship between age of onset of PD and PD-related cognitive changes; studies of neuroanatomical circuits and neurochemical processes mediating cognitive states and cognition-based individual differences in PD; examination of the specific consequences of deep brain stimulation or other surgical interventions on the cognitive aspects of PD; and development of assessment tools for detection of early cognitive change in people with PD.
For more information, potential applicants should contact Dr. Debra Babcock, Program Director, Systems and Cognitive Neuroscience Cluster, NINDS, Neuroscience Center, 6001 Executive Boulevard, Room 2108, Bethesda, MD 20892; telephone: 301-496-9964; fax: 301-402-2060; e-mail: email@example.com; or Dr. Diane Murphy, Program Director, Neurodegeneration Cluster, NINDS, Neuroscience Center, 6001 Executive Boulevard, Room 2222, Bethesda, MD 20892; telephone: 301-496-5680; fax: 301-480-1080; e-mail: firstname.lastname@example.org.
*For a more detailed description of this announcement, please visit the NIH web site at: http://grants.nih.gov/grants/guide/pa-files/PA-06-194.html (R03), or http://grants.nih.gov/grants/guide/pa-files/PA-06-195.html (R21).