The National Institute of Neurological Disorders and Stroke (NINDS), the National Heart, Lung, and Blood Institute (NHLBI), and the Institute of Circulatory and Respiratory Health (CRH) of the Canadian Institutes of Health Research (CIHR) invite applications to participate in the Network for Cardiothoracic Surgical Investigations in Cardiovascular Medicine-a cooperative network of academic centers with clinically active cardiothoracic surgeons and their colleagues in allied specialties interested in promulgating the use of evidence-based medicine in surgical practice. *
The goal of the network is to foster a culture of rigorous scientific comparisons and promote the evaluation of newer surgical techniques, technologies, devices, and innovative pharmaceutical and bioengineered products directed at cardiovascular disease. The network will allow research teams to evaluate newer therapies and techniques as they move from laboratory science to broad clinical use, and will enhance the capacity to disseminate study results, and translate findings to large-scale trials or practice. The program will provide support to maintain the necessary infrastructure to develop, coordinate, and conduct multiple collaborative proof-of-concept clinical studies and interventional protocols to improve cardiovascular disease outcomes.
Research topics include, but are not limited to: neuroprotective techniques, agents and devices to prevent central nervous system complications of cardiac surgery; studies comparing minimally invasive surgery to catheter-based ablation approaches for the treatment of chronic atrial fibrillation; clinical testing of new heart valve repair techniques; clinical testing in adults with congenital heart disease of surgery to treat atrial and ventricular arrythmias; trials of new computer-enhanced modalities for imaging, instrumentation, and robotics for minimally invasive cardiac surgery; and clinical studies of peri-operative techniques and/or drugs to reduce injury from spinal cord ischemia in patients undergoing repair of thoracic and thoraco-abdominal aortic conditions, including aortic dissections and aneurysms.
Letters of Intent Receipt Date: July 28, 2006
Application Receipt Date: August 28, 2006
For more information, potential applicants should contact Dr. Claudia Moy, Clinical Research Project Manager, Clinical Trials Group, NINDS, Neuroscience Center, 6001 Executive Boulevard, Room 2214, Bethesda, MD 20892; telephone: 301-496-2789; fax: 301-480-1080; e-mail: email@example.com.
*For a more detailed description of this announcement, please visit the NIH web site at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-06-005.html.