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Funding News - Research Sought on Diet Composition and Energy Balance

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  • The information on this page is for historical and research purposes only.
  • For the most current NINDS funding announcements, please see the NINDS list of Active Funding Initiatives or Follow Us on Twitter for the latest funding news.

The National Institute of Neurological Disorders and Stroke (NINDS) invites grant applications for research on diet composition and energy balance. This announcement is made together with 8 other components of the National Institutes of Health (NIH) and is supported by 2 grant funding mechanisms: R21 and R01.*

Overweight and obesity have increased dramatically in prevalence in the United States. More than 60 percent of the U.S. population is overweight. Environmental changes over the past two decades have increased sedentary behaviors, decreased physical activity, and increased consumption of more energy-dense foods and larger portion sizes. Although an imbalance in energy-consumption and expenditure is required to promote inappropriate weight gain, the relative contributions of each to the burgeoning obesity epidemic remain in dispute.

Topics of research interest include, but are not limited to: the impact of diets varying in levels of protein, carbohydrate, fat, phytochemicals, or ethanol on appetite, food selection and intake, and energy expenditure; the impact of diet composition on neuroendocrine, gastrointestinal, and other factors that may impact energy balance; brain imaging studies in humans and non-human primates to assess positron emission tomography, functional magnetic resonance, or cerebral blood flow imaging responses to specific dietary constituents; development of methods to assess dietary composition; dietary composition effects on the magnitude and time course of neurobehavioral and physiological responses to sleep loss, and the interaction of these effects with BMI, gender, age, and ethnicity; and life-stage, racial/ethnic, and gender-related factors underlying response to diet composition, including studies in children, adolescents, and adults of various ages.

For more information, potential applicants should contact Dr. Merrill Mitler, Program Director, Systems and Cognitive Neuroscience Cluster, NINDS, Neuroscience Center, 6001 Executive Boulevard, Room 2116, Bethesda, MD 20892; telephone: 301-496-9964; fax: 301-402-2060; e-mail:

*For a full list of supporting NIH components and a more detailed description of this announcement, please visit the NIH web site at: (R21), or (R01).