The National Institute of Neurological Disorders and Stroke (NINDS) and the National Institute on Aging (NIA) invite applications for collaborative awards in epilepsy research for junior investigators.*
Epilepsy, characterized by repeated uncontrolled seizures, is one of the most common neurological disorders in the United States. It currently afflicts approximately 15 million Americans of all ages and backgrounds. Despite many decades of research, new anticonvulsant drugs, and advances in surgical therapy, a large number of people with epilepsy suffer from uncontrolled seizures or the side effects of drugs or surgical treatment.
Potential research areas include, but are not limited to: mechanisms for interrupting or modifying the process of epileptogenesis; identification and characterization of genetic mutations that are the basis of inherited forms of epilepsy and that can provide a means of understanding the causes of seizures and determining treatment strategies; studies of the basic biology of neural development and aging that might contribute to identification of the molecular basis for abnormalities observed in some people with epilepsy; visualization of structural and functional changes in the brains of people with epilepsy using advanced imaging technologies such as magnetic resonance spectroscopy, functional magnetic resonance imaging, and magnetoencephalography; development of new classes of pharmacological agents and other effective therapeutic strategies such as focal brain stimulation and brain irradiation; and innovative clinical trial methodologies to quickly identify effective antiepileptogenic interventions.
For more information, potential applicants should contact Margaret Jacobs, Program Director, Channels, Synapses, and Circuits Cluster, NINDS, Neuroscience Center, 6001 Executive Boulevard, Room 2138, Bethesda, MD 20892; telephone: 301-496-1917; fax: 301-402-1501; e-mail: firstname.lastname@example.org.
*For a more detailed description of this announcement, please visit the NIH web site at: http://grants.nih.gov/grants/guide/pa-files/PA-06-190.html.