Scientists at the National Institute of Neurological Disorders and Stroke (NINDS) seek persons with Tourette syndrome (TS) for a research study of sensory symptoms such as clothing discomfort and premonitory urge.
TS is a neurological disorder that causes people to have uncontrolled movements, called “tics.” A tic can also be vocal, like a cough or a bark, or even as severe as a string of bad words. In either case, before a person with TS actually has a tic, they often feel the urge to tic. This is similar to feeling an urge to scratch an itch. Sometimes people with TS experience other sensations, such as a tickling feeling on the skin or a discomfort with certain clothing items. In this study, NINDS scientists will observe brain activity during the time of these sensations and how it may differ in people who have TS and people who do not have TS.
Participants in the study will undergo a non-invasive procedure called a magnetoencephalogram (MEG) which records the magnetic field changes produced by brain activity.
Eligible persons should have a diagnosis of TS and be between the ages of 14 and 65. Persons who have metal objects implanted in their bodies or have been diagnosed with certain neuropsychiatric disorders other than TS, or who are pregnant or taking certain medications, may not be eligible.
The one-day outpatient study will take place at the National Institutes of Health (NIH)
For more information, contact Rachel Wurzman, Human Motor Control Section, NINDS, Building 10, Room 5N240, 10 Center Drive MSC 1440, Bethesda, MD 20892-1440; telephone: 301-402-3493; fax: 301-480-2909. Please refer to study number 05-N-0230.