The National Institute of Neurological Disorders and Stroke (NINDS) invites grant applications for research on sleep and sleep disorders. This announcement is made together with 12 other components of the National Institutes of Health (NIH).*
An estimated 70 million people in the United States suffer from sleep problems, and more than 50 percent of them have a chronic sleep disorder. Despite substantial scientific progress in both clinical and basic science related to sleep and its disorders, there remains the challenge and the need to better understand the functions and disorders of sleep, treat sleep disorders, and explain the nature of human physiology during wakefulness and the individual stages of sleep.
Areas of potential research interest include, but are not limited to: neurobiological mechanisms of the effects of sleep, circadian regulation, sleep homeostasis, and sleep disorders on the aging process and the diseases associated with late age; methods to measure sleep, circadian physiology, and sleepiness across the age spectrum, including methods used in the home; studies of the mechanisms by which sleep disturbances affect adherence to treatments for chronic disease and ways that improving sleep may improve treatment outcomes; improved understanding of the processes that lead to specific sleep disorders in infants, children, and adults, including the aged population; impact of sleep-disordered breathing and its treatment on functional status, psychiatric disorders, neurocognitive function and behavior, and other disease processes; interrelationships between sleep and neuroendocrine systems, including aging male and female populations; new treatments for sleep disorders, including methods to adapt these therapies to individual patients using approaches such as pharmacogenetics; complementary and alternative medicine therapies for sleep disorders; neurophysiology of sleep regulation affecting risk for and mechanisms of sleep disorders in women in relation to menarche, pregnancy, or menopause; sleep in neurodegenerative disorders including, but not restricted to, Parkinson's disease; and sleep in neuropathic pain conditions.
For more information, potential applicants should contact Dr. Merrill Mitler, Program Director, Systems and Cognitive Neuroscience Cluster, NINDS, Neuroscience Center, 6001 Executive Boulevard, Room 2108, Bethesda, MD 20892; telephone: 301-496-9964; fax: 301-402-2060; e-mail: firstname.lastname@example.org.
*For a full list of supporting NIH components and a more detailed description of this program announcement, please visit the NIH web site at: http://grants.nih.gov/grants/guide/pa-files/PA-05-046.html.