The National Institute of Neurological Disorders and Stroke (NINDS) encourages grant applications for research on functional links between the immune system, brain function, and behavior. This announcement is made together with 5 other components of the National Institutes of Health (NIH).*
The purpose of this program announcement is to identify research opportunities that may bridge the gap in understanding how immune cells and their mediators affect brain development, function, and behaviors related to cognition and mood.
Areas of research interest include, but are not limited to: characterization of pathways that mediate the effects of peripheral and central immune activation on the brain across the lifespan; physiological and behavioral actions of immune cells and molecules; development and refinement of animal models of immune signaling in the brain; development and refinement of research tools to examine how immune molecules affect brain function and behavior; genetic determinants of immune responses in the brain; and clinical applications. Also encouraged are studies of the effects of immune molecules and cells on molecular and cellular neural processes, neuronal signaling, glial-neural interactions, neural activation, and objective behavioral endpoints of relevance to mood, cognition, and motivation. Studies examining immune effects on neurodevelopment and across the lifespan as well as studies comparing effects in males and females are also of interest.
For more information, potential applicants should contact Dr. Ursula Utz, Program Director, Neural Environment Cluster, NINDS, Neuroscience Center, 6001 Executive Boulevard, Room 2134, Bethesda, MD 20892; telephone: 301-496-1431; fax: 301-480-2424; e-mail: email@example.com.
*For a full list of supporting NIH components and a more detailed description of this program announcement, please visit the NIH web site at: http://grants.nih.gov/grants/guide/pa-files/PA-05-054.html.