Investigators at the National Institute of Neurological Disorders and Stroke (NINDS) are seeking persons affected with adductor or abductor spasmodic dysphonia to participate in research studies to improve understanding of the physiological basis for these disorders.
Some studies are part of an overall effort to determine the role of sensory feedback from the larynx to the brain in the generation of voice breaks. Different methods are being used to evaluate the role of laryngeal sensation in symptom generation. Additional studies use non-invasive techniques for measuring speech physiology in abductor spasmodic dysphonia and include assessment of a new treatment approach for this disorder.
Eligible participants must be between 18 and 70 years of age and have either adductor or abductor spasmodic dysphonia or muscular tension dysphonia. Participants should be without a history of cardiac problems, asthma, or pulmonary disease. They must not be currently receiving treatment for their voice disorder and cannot have had treatment during the previous 4 months.
The studies will be conducted at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD. All study-related expenses will be paid by the NIH. The studies will be carried out under testing and safety standards of the Department of Health and Human Services.
For more information, interested persons may contact Dr. Christy Ludlow and their physicians should send a referral letter and a copy of their recent medical records to Dr. Ludlow, NINDS, NIH, Building 10, Room 5D38, 10 Center Drive MSC 1416, Bethesda, MD 20892-1416; telephone: 301-496-9366; fax: 301-480-0803; e-mail: Ludlowc@ninds.nih.gov.