The National Institute of Neurological Disorders and Stroke (NINDS) invites grant applications for research studies on zebrafish as an animal model for development and disease research. This announcement is made together with 16 other components of the National Institutes of Health (NIH).* As a vertebrate, the zebrafish is more closely related to humans than are yeast, worms, or flies. Many features of zebrafish development have been characterized, including early embryonic patterning, early development of the nervous system, and aspects of cell fate and lineage determination. The zebrafish has a number of valuable features as a model organism for the study of vertebrate development. Examples of potential areas of interest include research on neurogenesis, nervous system patterning, cell lineage, cell migration, programmed cell death, axon pathfinding and regeneration, myelination, and cognitive, motor, and sensory function. Analyses of mutants that may serve as models for neurological disorders are also encouraged. For more information, potential applicants should contact Dr. Robert Finkelstein, Program Director, Neurogenetics Cluster, NINDS, Neuroscience Center, 6001 Executive Boulevard, Room 2136, Bethesda, MD 20892; telephone: (301) 402-1501; fax: (301) 496-5748; e-mail: firstname.lastname@example.org.
*For a full list of supporting NIH components and a more detailed description of this program announcement, please visit the NIH web site at: http://grants.nih.gov/grants/guide/pa-files/PA-01-095.html.