The National Institute of Neurological Disorders and Stroke (NINDS), the National Institute on Aging (NIA), and the National Institute of Mental Health (NIMH) request applications for research studies on gene discovery for neurological and neurobehavioral disorders.
The objective of this request for applications (RFA) is to promote the identification of genes that cause or contribute to human neurological and neurobehavioral diseases. This RFA is intended to encourage applications for genetics research projects with objectives such as identifying the gene or genes that produce disease susceptibility, identifying “modifier” genes that affect disease susceptibility or outcome, and/or investigating the relationship between genotype and disease phenotype.
Areas of potential research include: traditional linkage analysis; sib-pair and affected-pedigree-member methods; case-control or family-based association studies; linkage disequilibrium mapping in genetically isolated populations; candidate gene analysis; cytogenetic studies to identify chromosomal abnormalities associated with a disorder; and positional cloning techniques.
APPLICATION RECEIPT DATE: July 10, 2001.
For more information, potential applicants should contact Dr. Robert Finkelstein, Program Director, Neurogenetics Cluster, NINDS, Neuroscience Center, 6001 Executive Boulevard, Room 2136, Bethesda, MD 20892; telephone: (301) 402-1501; fax: (301) 496-5748; e-mail: rf45c@nih.gov.
For a more detailed description of this RFA, please visit the NIH web site at: http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-02-002.html.