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Funding News - High Throughput Screening

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  • The information on this page is for historical and research purposes only.
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NIH encourages applications for assay development for high throughput molecular screening (HTS). 

This program announcement is an NIH Roadmap Initiative.  The NIH Roadmap is an innovative approach to accelerate fundamental discovery and translate that knowledge into effective prevention strategies and new treatments.  All NIH institutes and centers participate in Roadmap Initiatives.

HTS is the automated, simultaneous testing of thousands of distinct chemical compounds in models of biological mechanisms.  Active compounds identified through HTS can provide the starting point for designing powerful research tools that allow pharmacological probing of basic biological mechanisms.  These tools also can be used to establish the role of a molecular target in a disease process or its ability to alter the metabolism or toxicity of a therapeutic agent.  The goal of this announcement is to support the development of novel, scientifically and technologically outstanding assays that can be miniaturized, automated, and further used for screening small molecules against structurally diverse libraries.

Potential applicants should contact Dr. Mark Scheideler, Senior Scientific Officer, Technology Development, NINDS; telephone: 301-496-1779; email: scheidelerm@ninds.nih.gov.  For a more detailed description of this announcement, visit http://grants.nih.gov/grants/guide/pa-files/PAR-08-024.html.  For more information on the NIH Roadmap, visit http://nihroadmap.nih.gov/.

High Throughput Screening Announcement

NIH invites applications for assays for high throughput screening to support the molecular libraries screening network (MLSCN).  This announcement is supported by two funding mechanisms:  R03 and X01.

This program announcement is an NIH Roadmap Initiative. The NIH Roadmap is an innovative approach to accelerate fundamental discovery and translate that knowledge into effective prevention strategies and new treatments. All NIH institutes and centers participate in Roadmap Initiatives.

The purpose of this announcement is to solicit high throughput screening assays from the scientific community by identifying investigators who have the interest and capability to work with the MLSCN in support of chemical probe development.  The MLSCN offers biomedical researchers access to large-scale automated screening centers, diverse compound libraries, and information on biological activities of small molecules.

Potential applicants should contact Dr. Ingrid Li, Molecular Libraries Assay Access Team, NIH Molecular Libraries and Imaging Roadmap, National Institute of Mental Health (NIMH); telephone: 301-443-5288; email: ili1@mail.nih.gov.  For a more detailed description of this announcement, visit http://grants.nih.gov/grants/guide/pa-files/PAR-08-035.html or http://grants.nih.gov/grants/guide/pa-files/PAR-08-034.html.  For more information on the NIH Roadmap, visithttp://nihroadmap.nih.gov/.