Researchers at the National Institute of Neurological Disorders and Stroke (NINDS) seek families with DYT1 dystonia (the most common type of familial generalized dystonia) to participate in a study. The purpose of this study is to understand how the brain controls movement and how this process is altered in DYT1 dystonia.
Eligible subjects include those with DYT1 positive gene status with dystonia, DYT1 carriers who have positive gene status but have no symptoms of dystonia, and family members who are non-carriers. The study, which involves a painless technique called transcranial magnetic stimulation (TMS) and lasts approximately 1-2 hours, will take place at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD. All study-related expenses will be paid by the NIH.
For more information, physicians should contact Dr. Fiona Molloy, Office of the Clinical Director, NINDS, NIH, Building 10, Room 5N236, 10 Center Drive MSC 1428, Bethesda, Maryland 20892-1428, telephone: 301-594-0937.