Investigators at the National Institute of Neurological Disorders and Stroke (NINDS) seek patients with syringomyelia for studies of the pathophysiology of the disorder. Patients will undergo testing both before and after receiving surgical treatment for this condition.
To be eligible, patients must be 18 to 70 years old and must have syringomyelia associated with a pathologic process at the craniocervical junction, such as Arnold-Chiari malformation. Prior surgery does not exclude patients from the trial, but patients who are pregnant or are suffering from bleeding disorders will not be accepted. This study will take place at the National Institutes of Health (NIH) Clinical Center, Bethesda, MD. All treatment-related expenses will be paid by the NIH.
For more information, physicians should contact Dr. Edward H. Oldfield, Chief, Surgical Neurology Branch, NINDS, NIH, Building 10, Room 5D37, 10 Center Drive MSC 1414, Bethesda, MD 20892-1414; telephone: (301) 496-5728.