This contract is to identify two NINDS "Facility of Research Excellence in Spinal Cord Injury" (FORE-SCI) sites to conduct research to replicate promising studies that could lead to new and effective treatments for SCI. The role of these two FORE-SCI centers will be to independently review and replicate novel treatments for SCI and to compare the efficacy of different treatments in a standardized environment with a minimum of variability in surgery, animal care, outcome evaluation and cellular analyses.