Morris K. Udall Centers of Excellence for Parkinson’s Disease Research (P50)
Funding Contact(s): Beth-Anne Sieber, Ph.D.
Funding Categories: Neurodegeneration
Brief Description:
The National Institute of Neurological Disorders and Stroke (NINDS) invites new and renewal applications for the Morris K.
Udall Centers of Excellence for Parkinson’s Disease Research program. The overarching goal of the specialized Udall Centers
program is to establish a network of Centers that work independently as well as collaboratively to define the causes of and
discover improved treatments for Parkinson’s disease (PD). A more immediate goal for each Center is to rapidly advance synergistic
basic, translational and clinical research programs while serving as local resources and national leaders in PD research.
The overall theme, proposed research projects, and associated cores must relate directly to the etiology, pathogenesis or
treatment of PD. Investigations on related parkinsonian disorders may be included, to the extent that these directly inform
research on PD. Required components include: 1) a minimum of three interdisciplinary research projects, with at least one
translational research project focusing on the development of therapeutics, diagnostics, devices or clinical criteria that
would ultimately lead to new approaches for the treatment of PD; 2) Cores that are essential to accomplish the Aims of proposed
research projects, plus an Administrative Core; and 3) a specific plan to provide for training (as a separate Core or within
the Administrative Core). Because basic research serves as the foundation for discovery in the Udall Centers program, preference
will be given to applications that propose a basic research project. A considerable degree of synergy must be evident among
Center research projects and Cores, such that successful completion of the Aims requires the support of the Center structure.
The Udall Center Director (PD/PI) must be an established leader in scientific research with visionary leadership skills and
proven expertise in research project and personnel management. Eligible institutions must demonstrate commitment to and support
for the establishment and continuation of the proposed Udall Center. Funding decisions will focus on those applications evincing
the capacity for innovative contributions to PD research, as well as the potential to contribute new ideas and collaborate
effectively across the Centers program. Successful applicants will participate in a network of existing Udall Centers to foster
the translation of scientific findings and technological developments into novel treatments for PD. Contact with the NINDS
program officer at early stages of program planning is encouraged.