The Office of Research Integrity (ORI, DHHS) and the National Institute of Neurological Disorders and Stroke (NINDS, NIH) invite applications (R01) to support research on research integrity. "Integrity" in this context is understood as "adherence to rules, regulations, guidelines, and commonly accepted professional codes or norms." Research integrity is a vital component both of the reliability of the research record and of the trust that underlies public support for research. Therefore the responsible expenditure of public funds for research must include attention to research integrity. The purpose of the proposed grant program is to foster empirical research on the institutions, processes, and values that affect integrity in research. The sponsoring agencies are particularly interested in studies that will inform policy making at DHHS, NIH, and research institutions, with the goal of fostering appropriate attention to integrity in publicly funded research programs.