NINDS Neuroscience Funding Announcements

Identifying Autism Susceptibility Genes

Funding Contact(s): Laura Mamounas, Ph.D.
Funding Categories: Neurogenetics

Brief Description:
The goal of this Request for Applications (RFA) is to solicit applications to identify specific genes and gene variants in localized chromosomal regions that confer susceptibility to autism. Fine mapping of disease loci, or quantitative trait loci (QTLs), is expected to occur in very large datasets of pre-existing samples that have high statistical power for fine mapping autism susceptibility loci. In order to improve the probability of obtaining biologically and clinically meaningful associations between genotypes and disease outcomes, this initiative will not be limited to fine-scale mapping of a disease locus but will proceed to the next level of positional identification of strong candidate genes via assessment of the functional significance of the autism - associated genetic variants.

NIH Guide: RFA-MH-05-007
Release Date: 2004-12-13
Expiration Date: 2005-04-20