This Funding Opportunity Announcement (FOA), issued by NICHD, NINDS, and NIBIB, National Institutes of Health, solicits grant applications from institutions/organizations that propose to build research infrastructure for medical rehabilitation. The aim of this FOA is to create a national network of research cores that provide access to collateral expertise in biomedical, behavioral, and/or psychosocial fields that are particularly relevant to medical rehabilitation research. Applicants should propose a program of research resources and collaborative opportunities in a specific content area. This may be accomplished through a combination of didactic interactions (workshops, courses, written material, and websites), consultations, and pilot funding. In addition, the research core may support intramural activities related to technique development, adaptation, and validation. Although examples of relevant expertise and content are provided below, additional areas may be proposed provided they have potential for promoting medical rehabilitation research and improving outcomes for people with disabilities.