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NINDS Neuroscience Funding Announcements



Development and Improvement of Inbred ES Cell Lines for Use in Generation of Mouse Mutants

Funding Contact(s): Robert Riddle, Ph.D.
Funding Categories: Neurogenetics

Brief Description:

The purpose of this RFA is to develop C57BL/6 ES cell lines that are efficient for high-throughput gene targeting and in successfully generating mice that can transmit the targeted mutation through the germline, both steps being necessary to create knockout mice on a C57BL/6 background. This RFA is a companion to two other RFAs (HG-05-007 and HG-05-008), all three of which are part of the NIH Knockout Mouse Project (KOMP).



NIH Guide: RFA-DA-06-009
Release Date: 2005-09-16
Expiration Date: 2005-11-22