Understanding and Treating Tuberous Sclerosis Complex (R01)
Funding Contact(s): Jane Fountain, Ph.D.
Funding Categories: Neural Environment
Brief Description:
Inviting research grant applications aimed at understanding or treating Tuberous Sclerosis Complex (TSC). The genes that cause
TSC (TSC1 and TSC2) are known, understanding of the pathways in which they act is increasing, and animal models that mimic
certain features of the disease now exist. As a result, there is a remarkable opportunity to increase our knowledge about
the mechanisms that cause TSC and translate this knowledge into therapies for this often devastating disorder. Included within
the scope of this PA are molecular genetic, developmental, and pathophysiological studies, preclinical therapy development
and clinical research.