This funding opportunity announcement (FOA) supports applications from organizations that propose neuroscience research education programs that will significantly advance the mission of the NINDS. The NIH Research Education (R25) grant mechanism is designed to support the development and implementation of creative and innovative neuroscience research education programs for biomedical, behavioral, and clinical researchers. Proposed research education programs submitted to this FOA are expected to be designed for, and available to, a national audience. Programs intended for a local or regional audience are not appropriate for this FOA. R25 programs may complement ongoing research training and education occurring in the U.S., but the proposed educational experiences must be distinct from those research training and research education programs currently receiving federal support. The R25 is not a substitute for an institutional research training program (T32) and cannot be used to circumvent or supplement Ruth L. Kirschstein National Research Service Award (NRSA) mechanisms. Moreover, it is not intended to fund conferences or other workshops that were previously funded by, or are appropriate for support by, the R13/U13 mechanism.