Innovation in Molecular Imaging Probes (R01)
Funding Contact(s): Ursula Utz, Ph.D.
Funding Categories: Neural Environment
Brief Description:
This FOA is issued by the National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health. This
FOA is a follow up of a previous Roadmap RFA (RM-04-021 “Innovation in Molecular Imaging Probes”). The purpose of this initiative
is to encourage the development of novel molecular imaging approaches that can detect and image specific molecular activities
in vivo, and have the potential for clinical applications. Novel molecular imaging approaches developed through this initiative
can focus on one (or both) of the following long-term translational goals: (1) imaging the characteristic markers, and function,
of normal cells in control human subjects and patients, and (2) imaging the characteristic markers, and biochemical or physiological
abnormalities, of disease cells in patients. Potential abnormalities that could provide early markers for disease include
(but are not restricted to): inflammation, fibrosis, immune cell activation, altered signal transduction pathways, altered
gene expression pathways, and altered post-translational modification of proteins. This initiative solicits applications
that explore innovative “high-impact” approaches, rather than incremental technology development that is already supported
by current NIH programs.