Sharing data and tools across a research community adds tremendous value to the efforts of that community. Search engines like Google show the power of sharing text based data. While strides have been made, the infrastructure necessary to share and query data sets that have more than just textual biomedical data is still under development. Examples of such heterogeneous data sets include those that contain images, clinical data, or genomic/gene expression data. Two large NIH supported infrastructure projects to allow data and tool sharing are the caBIG™ program and the Biomedical Informatics Research Network (BIRN).