Research at the borders of disciplines and from fresh perspectives often produces surprising and exciting results. Increasingly, teams of scientists from diverse disciplines converge on a common research questions. Individuals who can independently bridge different disciplines, as well as those who are able to function as leading members of multi-disciplinary research teams are playing ever more valuable roles at the forefront of biomedicine. The purpose of the Mentored Quantitative Research Career Development Award (K25) is to engender and foster such activities by supporting the career development of investigators with quantitative scientific and engineering backgrounds outside of biology or medicine who have made a commitment to focus their research endeavors on behavioral and biomedical research (basic or clinical). This mechanism is aimed at research-oriented scientists with experience at the level of junior faculty (e.g., early to mid-levels of assistant professor or research assistant professor ranks). This award provides support for a period of supervised study and research for professionals with such backgrounds who have the potential to integrate their expertise with biomedicine and develop into productive investigators.