The purpose of this notice is to (1) announce the issuance of the SOLICITATION of THE NATIONAL INSTITUTES OF HEALTH (NIH), CENTERS for DISEASE CONTROL AND PREVENTION (CDC), and FOOD AND DRUG ADMINISTRATION FDA) for SMALL BUSINESS INNOVATION RESEARCH (SBIR) and SMALL BUSINESS TECHNOLOGY TRANSFER STTR) GRANT APPLICATIONS (PHS 2004-2) and (2) inform the public about the opportunities that the SBIR/STTR programs offer to small business concerns. The NIH, CDC, and FDA invite eligible small business concerns to submit Phase I grant applications for the Calendar Year (CY) 2004 SBIR program and, applicable to NIH only, for the STTR program.