The purpose of this Notice is to inform the community that the National Institutes of Health is implementing an alternate plan for receipt and review of X01 applications seeking access to the NeuroNEXT infrastructure to conduct clinical trials in neurological diseases: PAR-11-344, NeuroNEXT Infrastructure Resource Access (X01). This alternate receipt and review plan is not applicable to PAR-11-343, NeuroNEXT Clinical Trials (U01) or PAR-11-345, NeuroNext Small Business Innovation in Clinical Trials (U44). Interested parties should look at those announcements for the applicable receipt dates.